Joseph A. Sinkule has been appointed director of research and development for Techniclone International Corp. in Tustin. Previously, Sinkule was assistant director of clinical affairs for Immunex R&D Corp. of Seattle. Before entering industry, he was assistant professor of radiation oncology and co-director of the Immunoconjugate Laboratory at the University of Michigan Medical Center. In addition, William Borner has been named director of quality assurance and regulatory affairs for Techniclone. Most recently Borner was director of operations for Westminster-based Innatech Medical Laboratories/Dow Corning Wright. Techniclone develops and manufactures specialized antibodies that are used in treating and diagnosing cancer.