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O.C. Children's Hospital in Battle With Star Doctor

Medicine: Cancer specialist has been stripped of key posts. He blames business difficulties involving prior administrator.


ORANGE — Not long ago, Dr. Mitchell S. Cairo gained prominence as one of the best things that ever happened to kids with cancer in Orange County.

The specialist at Children's Hospital of Orange County treated baseball Hall of Famer Rod Carew's dying daughter. Last year, he appeared on the "Today" show and gained national repute for himself and the hospital as he struggled in vain to save her with an experimental transplant of umbilical cord blood.

But now the only hospital in the county for children is locked in a battle with its most famous doctor that has raised questions about research practices and the financial future of the hospital.

* In January, the hospital abruptly stripped Cairo of several key posts, and succeeded in pressuring him to step down as chairman of a medical group he led for more than a dozen years. The group is responsible for much of the hospital's revenue.

For the Record
Los Angeles Times Saturday May 24, 1997 Orange County Edition Part A Page 5 Metro Desk 2 inches; 37 words Type of Material: Correction
Children's Hospital--An article Wednesday about Children's Hospital of Orange County and one of its cancer specialists incorrectly reported plans for a scheduled meeting about a possible affiliation with St. Joseph Hospital. No meeting has been scheduled.

* The hospital continues a lengthy review of Cairo by his medical peers that led to a temporary suspension of his hospital privileges. Hospital officials said he has since regained his privileges.

Although the reason for these actions remains a mystery, a recent federal audit criticized the hospital--and Cairo as its principal investigator--for putting patients on government-supported research studies and taking them off inappropriately, according to a summary of the audit obtained by The Times. As a result, Cairo was suspended from his top research role for the group that runs the studies, although he has retained other titles with the research group.

Cairo blames what he calls a few detractors who chafed during his years of leadership. He says the campaign against him was touched off by business difficulties between the medical group and the hospital's former chief executive officer, Thomas Penn Jones, who resigned abruptly in late January. Attempts to reach Jones for comment were unsuccessful.

"Any of these allegations and the inquiries associated with them were not conducted in a fair-minded way," said Cairo, 46.

"The present administration has been very reasonable and I think will bring most of these issues to a close in a very short period of time, and I will be vindicated."

Cairo says he considers the audit findings minor, and is appealing the resulting suspension.

The hospital's falling-out with its star researcher is worsening what are already the toughest times in the hospital's history:

* The hospital estimates that it will post a loss of $13.1 million for the fiscal year ending June 30--the worst in its 33 years and nearly double last year's losses.

* Department heads have just been ordered to slash their budgets by 15%. And the boards of trustees of the hospital and neighboring St. Joseph Hospital plan to meet this week to consider "a close affiliation" that would fall just short of a merger, an insider said.

* The hospital has temporarily closed its oncology intensive care unit for lack of patients but says it plans to reopen it by the end of the month. Overall, patient admissions have dropped by 25% over the past five years.

* In its struggle with Cairo, the hospital has alienated some major donors who have threatened to pull their support because of the way the doctor was treated.

Cairo was the first doctor in Orange County to perform transplants of "stem" cells--culled from bone marrow, cord blood and the like--to restore a child's immune system. The hospital remains the only place in the county where such transplants are available.

But as of January, Cairo no longer is head of the transplant program, and the number of such transplants has plummeted from a high of 34 in 1995 to four in the past eight months.

The hospital hired Cairo in 1981 to make its name in cancer research.

Cairo and his staff published prolifically in scientific journals, boosting the hospital's visibility and landing it membership in Children's Cancer Group, an elite federally funded national cooperative of leading researchers. He became the principal investigator for the cancer group's program at the hospital.

Under his direction, the hospital racked up numerous firsts in Orange County--a bone marrow transplant in 1986; a bone marrow transplant from an unrelated donor in 1993; an umbilical cord blood transplant in 1995.

Cairo launched the hospital's fellowship program and expanded the Pediatric Subspecialty Faculty, a private physician's partnership of which he became chairman.

By 1995, he was the head of cancer research and directed the hospital's bone marrow transplant program.

But three physicians have filed suits in Orange County Superior Court against the hospital, Cairo and the rest of the medical partnership since 1995, alleging that they were denied access to the partnership's books under Cairo's leadership.

Cairo denies all the allegations.

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