* Irvine-based Cortex Pharmaceuticals Inc., which focuses on treatments for neurological and psychiatric disorders, reported a fourth-quarter net loss of $740,000, or 4 cents a share, contrasted with a profit of $1.2 million, or 7 cents a share, for the same period in 2000. Revenue fell nearly 62% to $1.1 million.
* Marc Ley has been named chief financial officer of the Irvine Co., and Dan Hedigan becomes senior vice president and general counsel. Ley, who had been the company's senior vice president of capital markets and chief investment officer, succeeds Mike McKee, who was promoted to chief operating officer this year. Hedigan has been the company's general counsel since 1996.
* Marvin Samson has been named president and chief executive officer of generic drug maker Sicor Inc. in Irvine. Samson joined Sicor's board about a year ago. He succeeds Carlo Salvi, the company's largest shareholder, who becomes vice chairman.