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Science File | IN BRIEF

New Drug Reduces 'Bad' Cholesterol Up to 44%

August 14, 2004|From Times Staff and Wire Reports

A new type of drug can reduce cholesterol levels significantly, the makers of the drug reported Wednesday. The drug works through a genetic method called anti-sense, said Carlsbad, Calif.-based Isis Pharmaceuticals.

Known by its experimental name, ISIS 301012 blocks production of a protein that carries low-density lipoprotein, the so-called bad cholesterol that causes heart disease. In 19 volunteers, the drug lowered LDL levels by as much as 44% after 25 days.

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