3 Die in Afghans' Anti-U.S. Protests

Thursday's rallies were by far the biggest anti-American protests in Afghanistan since the fall of the Taliban regime in 2001. Officials said two people were killed in the Khogyani district of Nangarhar province when police tried to disperse protesters and keep them from marching to Jalalabad, where four people were killed in similar demonstrations Wednesday.

Another person was killed in the capital of Wardak province, southwest of Kabul, as mobs clashed with police.

In neighboring Lowgar province, rioters ransacked the offices of CARE International, one of the largest aid groups in Afghanistan.

"A couple of our staff members were beat up and some of our computers were broken," said Paul Barker, the CARE director in Afghanistan. "But luckily no one was killed."

CARE evacuated its Lowgar staff to Kabul.

Newsweek magazine recently reported that U.S. interrogators at Guantanamo in at least one instance flushed a copy of the Koran down a toilet. Pakistan has formally protested the alleged desecration.

In Washington, Secretary of State Condoleezza Rice said the reports were being investigated by military authorities, and "if they are proven true, we will take appropriate action."

Rice urged Muslims to resist calls for violence. Her statements came at the start of testimony to U.S. lawmakers.

"We have heard from our Muslim friends around the world about their concerns on this matter. We understand and we share their concerns. Sadly, some people have lost their lives in violent demonstrations," she said.

"I want to speak directly to Muslims in America and throughout the world. Disrespect for the Holy Koran is not now, nor has it ever been, nor will it ever be, tolerated by the United States," she said.

In Kabul, about 300 university students shouted "Death to America!" and burned a U.S. flag.

"We want action taken against those who are trying to demean our great religion," said Abdul Moomen, a student of Islamic law and one of the protest organizers at Kabul University.

Other protesters called on President Hamid Karzai to "stop cooperating with countries that are trying to humiliate Muslims."