Gay Sex Called Key to Rise in Syphilis

Men engaged in risky homosexual activity are fueling a sharp increase in the incidence of syphilis and a smaller but worrisome rise in gonorrhea resistant to common antibiotics, federal researchers said Tuesday.

The increases are seen at a time when sexually transmitted disease rates among historically important risk groups, especially women and minorities, have been declining, according to a new report from the Centers for Disease Control and Prevention.

The diseases "are a significant and ongoing threat to millions of Americans," said Dr. Ronald O. Valdiserri, acting director of CDC's National Center for HIV, STD and TB Prevention. They cost the healthcare system $13 billion per year, he said.

Health authorities made major inroads into slowing syphilis transmission during the 1990s, bringing the annual number of new cases during 2000 to the lowest level since recordkeeping began in 1941.

Between 2000 and 2004, however, the rate rose by 29% to a total of 7,980 cases, with most of the increase occurring among men.

Men engaging in homosexual activities accounted for 64% of syphilis infections in 2004, compared with about 5% in 1999, said Dr. John M. Douglas Jr., director of the CDC's division of sexually transmitted disease prevention.

Although the number of cases is small, experts say the data are worrisome because increases in sexually transmitted diseases are thought to be precursors of increases in the transmission of the AIDS virus, which is much more difficult to combat.

"We have very good and sound information showing increases in high-risk behaviors among men having sex with men since 1999," fueling the increase in syphilis, Valdiserri said.

Risky behavior has increased because of growing crystal methamphetamine use, he said -- first on the West Coast and now on the East.

"That's exacerbating the transmission of syphilis," he said.

As in previous years, San Francisco had the highest incidence of syphilis, with a rate of 45.9 cases per 100,000 people. Atlanta was second with 34.6 cases, and Baltimore third with 33.2. Los Angeles ranked 24th, with five cases per 100,000.

Gonorrhea rates, in contrast, have fallen to 113.5 cases per 100,000 people in 2004 -- about 330,000 cases -- the lowest rate since 1941. Nonetheless, surveillance by the CDC in selected cities has shown that resistance to fluoroquinolone antibiotics -- the common first-line treatment for gonorrhea -- increased from 4.1% in 2003 to 6.8% in 2004.


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