`Biopharmed' Rice Reaps Resistance

SAN FRANCISCO — In its quest to genetically engineer rice with human genes to produce a treatment for childhood diarrhea, tiny Ventria Bioscience has made an astonishing number of powerful enemies spanning the political spectrum.

Environmental groups, corporate food interests and thousands of farmers across the country have succeeded in chasing the company's rice farms out of two states. And critics continue to complain that Ventria is recklessly plowing ahead with a mostly untested technology that threatens the safety of conventional crops grown for the food supply.

"We just want them to go away," said Bob Papanos of the U.S. Rice Producers Assn. "This little company could cause major problems."

Ventria, with 16 employees, practices "biopharming," the most contentious segment of agricultural biotechnology because its adherents essentially operate open-air drug factories by splicing human genes into crops to produce proteins that can be turned into medicines.

Ventria's rice produces two human proteins -- found in mother's milk, saliva and tears -- which help people hydrate and lessen the severity and duration of diarrhea attacks, a top killer of children in developing countries.

But farmers, environmentalists and others fear that such medicinal crops could cross-pollinate with conventional crops, making them unsafe to eat.

Ventria says the chance of its genetically engineered rice ending up in the food supply is remote because the company grinds the rice and extracts the protein before shipping. What's more, rice is self-pollinating, and it's virtually impossible for genetically engineered rice to accidentally crossbreed with conventional crops.

"We use a contained system," Ventria Chief Executive Scott Deeter said.

U.S. rice farmers in particular fear that important overseas customers in lucrative, biotechnology-averse countries such as Japan will shun U.S. crops if biopharming is allowed to proliferate. Exports account for 50% of the rice industry's $1.18 billion in annual sales.

Japanese consumers, like those in Western Europe, are still alarmed by past mad cow disease outbreaks mishandled by their governments, making them deeply skeptical of any changes to their food supply, including genetically engineered crops.

Rice interests in California drove Ventria's experimental work out of the state in 2004, after Japanese customers said they wouldn't buy the rice if Ventria were allowed to set up shop.


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