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In Brief

Gene mutation may raise ALS risk

December 22, 2007|From Times Staff and Wire Reports

A mutation in a single gene may confer up to a 30% higher risk of getting amyotrophic lateral sclerosis, or Lou Gehrig's disease, offering a potential new target for drug research, Dutch scientists said this week. They said in the journal Nature Genetics that a variant in the DPP6 gene may give rise to ALS in people without a family susceptibility to the disease. Familial ALS, which accounts for 10% of ALS cases, has been linked with mutations in other genes.

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