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Science Briefing

Vaccine aids fatal yeast infection

August 30, 2008|From Times Staff and Wire Reports

A vaccine helped mice fight off a life-threatening type of yeast infection called Candida albicans, U.S. researchers reported Monday in the Proceedings of the National Academy of Sciences.

Researchers from Children's Hospital in New Orleans developed a synthetic vaccine made from the yeast that incorporates both a carbohydrate and a protein from the yeast cell, offering the immune system two potential targets.

The researchers gave mice three doses of the vaccine and then challenged them with what is normally a lethal infection. Mice that had not received the vaccine died after 24 days, but the vaccinated mice got better.

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