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Accuracy of gender test kits in question

The modern-day equivalent of old wives' tales, they can have far greater consequences than inappropriately colored nurseries.

By Karen Kaplan, Los Angeles Times Staff Writer|February 24, 2008

Amid the tumult of the delivery room, Rohit and Geeta Jain were calm about one thing: Their new baby was sure to be a boy.

Six months earlier, the Jains had spent more than $300 for a test that screened a minute quantity of Geeta's blood for traces of male DNA. The testing company said it was 95% accurate in determining the sex of a baby, even as early as the eighth week of pregnancy.


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After six hours in the delivery room, Rohit gaped as his wife gave birth to a daughter.

"There's only two choices -- either it's a boy or a girl," said Rohit, 35, a computer scientist in the Vancouver, Canada, suburb of Surrey. "I couldn't fathom how it could be wrong."

Like scores of other expectant parents, the Jains had stumbled into a corner of the booming genomics industry and discovered that the claims of some genetic entrepreneurs have gone beyond what science can provide.

Marketing directly to consumers, the new crop of companies has jumped into a realm of dubious science, mining DNA to offer information on ethnic heritage, long-lost relatives, personalized dieting plans -- even the sports for which one is best suited.

The tests are loosely based on legitimate scientific research, much of which has been funded by the National Institutes of Health, among others. But often, the companies' claims of accuracy have not been backed up by independent laboratory analysis.

Thousands of consumers have bought tests -- and analysts say the number will only grow as entrepreneurs find more ways to market the mysteries of the human genome.

The Federal Trade Commission, which protects consumers from false and misleading advertising, has warned buyers to be skeptical of at-home genetic tests, which are now unregulated.

In most cases, customers have no way of judging if their test results are accurate. But if a prenatal gender test is wrong, parents will surely find out.

The tests, scientists say, are the latest incarnation of old wives' tales about salty food cravings, hairy legs and belly shapes denoting the sex of the impending baby. This time, the predictions are being sold with the patina of cutting-edge genetic technology.

A host of companies, such as Acu-Gen Biolab Inc. of Lowell, Mass., and Consumer Genetics Inc. of Sunnyvale, Calif., have been selling the tests for $249 and up. Critics say they are banking on most disgruntled parents being too happy -- or too busy -- with their new child to file for a refund.

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