The artery thickening was most advanced in patients who were the most obese and had the highest levels of a type of cholesterol known as triglycerides, so that combination "should be a red flag to the doctor that a child is at high risk of heart disease," she said. Their long-term prospects "are not good" unless they can reverse the condition.
The findings suggest the potential for "a major public health problem" down the road, said Dr. Albert Bove of the Temple University School of Medicine, president-elect of the American College of Cardiology, who was not involved in the study.
"If we begin to see people disabled in their 30s and 40s because of heart disease, we could lose a significant fraction of the workforce," Bove said.
But there is some hope.
"If we can identify the condition early and start modifying triglycerides, we can probably prevent progression and perhaps even promote regression," said Dr. John P. Kennedy, director of prevention cardiology at Marina del Rey Hospital.
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thomas.maugh@latimes.com