at No. 5 Virginia Tech 48, Boston College 14: Tyrod Taylor, Ryan Williams and the defense made sure the Hokies' (5-1, 3-0) regular-season losing streak against the Eagles (4-2, 2-2) ended.
at No. 11 Miami 48, Florida A&M 16: Jacory Harris led the Hurricanes (4-1) to 31 points playing only the first half, and Miami beat the Rattlers (4-1) for the seventh time in a row.
No. 22 Georgia Tech 49, at Florida State 44: Josh Nesbitt ran for three touchdowns and threw for another to lead the Yellow Jackets (5-1, 3-1) to a win against the Seminoles (2-4, 0-3).
Duke 49, at North Carolina State 28: Thad Lewis threw for career highs of 459 yards and five touchdowns to help the Blue Devils (3-3, 1-1) beat the Wolfpack (3-3, 0-2).
at Wake Forest 42, Maryland 32: Riley Skinner threw for 360 yards and a career-high four touchdowns, leading the Demon Deacons (4-2, 2-1) over the Terrapins (2-4, 1-1).
at Virginia 47, Indiana 7: Mikell Simpson ran for four touchdowns and cornerback Ras-I Dowling forced two turnovers to set up scores as the Cavaliers (2-3) defeated the Hoosiers (3-3).
at North Carolina 42, Georgia Southern 12: Ryan Houston rushed for three touchdowns, and Quan Sturdivant returned a fumble 49 yards for a score, and the Tar Heels (4-2) beat the Eagles (3-3).