Advertisement
 
YOU ARE HERE: LAT HomeCollectionsFeatures
(Page 2 of 2)

Diabetes drugs may leave heart at greater risk

A CLOSER LOOK: Type 2 diabetes medications

Working harder to lower blood glucose in Type 2 diabetics doesn't help the heart, studies say.

October 26, 2009|By Jill U Adams

But this reanalysis (which was presented at a diabetes meeting in June) still needs confirmation, says Dr. Victor Montori, a physician-researcher at the Mayo Clinic in Rochester, Minn. For his part, he thinks that tight glucose control may be getting far too much emphasis in the management of diabetes.

In an April paper in the Annals of Internal Medicine, he pointed to the dearth of benefits of tight glucose control in studies and advocated "good enough" glucose control instead. What this means would depend on the individual patient, Montori says, but would include weighing the benefits of sugar control against some of the undesirable effects of diabetes medications. Many of the drugs cause patients to gain weight, and they can often trigger hypoglycemia, a dip in blood sugar (to less than 70 mg/dL) that's accompanied by shaking, dizziness and sudden sweating.

Montori notes that a good-enough blood sugar strategy would also ease the sheer time and energy it takes to manage diabetes. Treatment regimens -- with frequent doses of pills or insulin, blood-sugar monitoring and doctor visits -- are complicated and burdensome, particularly in patients who may be elderly and have other chronic conditions, such as high blood pressure and high cholesterol. One estimate of the time patients spend taking care of their condition, if they follow all the advice of their doctors, is 143 minutes per day. "That's as much as a part-time job," Montori says.

health@latimes.com

Advertisement
Los Angeles Times Articles
|
|
|