Chuck: Chuck and Sarah (Zachary Levi, Yvonne Strahovski) go up against a ruthless spy (Rebecca Romijn) in their quest to take down a dangerous computer virus before it's too late in this new episode (8 p.m. NBC).
Extreme Makeover: Home Edition: Ty and the team head to Ohio to help build a home for the tight-knit family of a woman with a brain tumor (8 and 9 p.m. ABC).
Grimm: A brutal murder in the woods has Nick and Hank (David Giuntoli, Russell Hornsby) revisiting a long-ago disappearance in this new episode (9 p.m. NBC).
The Life & Times of Tim: The animated series returns for a new season (9 p.m. HBO).
Dateline NBC: In this new episode of the news magazine series, Lester Holt reports on the mysterious 2005 disappearance of Ray Gricar, a district attorney in Pennsylvania who investigated sex-abuse claims made against Jerry Sandusky in 1998 (10 p.m. NBC).
20/20: This new episode documents efforts to reduce the mortality rate during pregnancy and childbirth (10 p.m. ABC).
Invention USA: In back-to-back episodes the guys meet an inventor who has sacrificed everything on a device for scraping ceilings and then test an inflatable shelter to help people in natural disasters (10 and 10:30 p.m. History).
Christmas in Washington 2011: The Band Perry, Justin Bieber, Cee Lo Green, Jennifer Hudson and Victoria Justice take the stage at the National Building Museum for this year's edition of the annual holiday concert, a must-attend for the president and first lady and other D.C. dignitaries (8 p.m. TNT).
Christmas in Connecticut: A successful lifestyle journalist (Barbara Stanwyck) is lauded by her readers as the sweetest, most efficient homemaker in the countryside. Problem is, she's a chain-smoking urbanite. Dennis Morgan and S.Z. Sakall co-star in the 1945 romantic comedy (7 p.m. TCM).
Hockey: The Ducks visit the Chicago Blackhawks (5:30 p.m. FS Prime).