Andrew Bynum suffered a left ankle injury late in the first quarter and left the Lakers' game Sunday against the Golden State Warriors.
The Lakers called it a sprained ankle and X-rays were negative. He will not return Sunday and will be reevaluated Monday.
Bynum, who appeared to come down on another player's foot, had played 49 consecutive games since a four-game suspension to start the season.
He was averaging 18.3 points and 12.1 rebounds before Sunday's game. He was scoreless with three rebounds when he left with 1 minute 49 seconds to go in the first quarter.