Advertisement
YOU ARE HERE: LAT HomeCollectionsFertility

COLUMN ONE

Israel sperm banks find quality is plummeting

Sperm quality is down everywhere, but Israel is worse off than other developed countries. Theories about why vary from cellphones in pockets to estrogen in milk or water.

August 15, 2012|By Edmund Sanders, Los Angeles Times
  • Ruth Har-Nir, head of Hadassah Sperm Bank in Jerusalem, first noticed a decline in quality 10 years ago. Today the bank turns away about two-thirds of potential donors.
Ruth Har-Nir, head of Hadassah Sperm Bank in Jerusalem, first noticed a… (Edmund Sanders, Los Angeles…)

JERUSALEM — The founder of the Tel Aviv-based specialty firm raves about his product with the same gusto distillers reserve for their top-notch scotch. He's particularly proud of his "premium" line. Sure, it costs a bit more, but it's targeted at a more discriminating client.

Dr. Jacob Ronen is in the sperm business. Among other things, as head of Cryobank Israel, the country's largest private sperm bank, he guarantees that his stable of superior donors includes only tall, twentysomething ex-soldiers whose sperm has passed rigorous genetic testing.

But finding such super sperm isn't as easy as it used to be. Only 1 in 100 donors makes the cut. A decade ago, it was 1 in 10.

And it's not just first-rate sperm that's in short supply. All of Israel's half a dozen or so sperm banks are scrambling to keep their liquid-nitrogen freezers stocked.

Simply put, the quality of Israeli sperm is falling at an alarming rate, and no one's sure exactly why.

Fertility is a major issue in Israel, where memories of the Holocaust genocide are fresh, and having children is an entrenched part of Judaism. There's also a political aspect, because birthrates among Arabs in Israel have at times been as much as double those of Jews, triggering a population race that some believe could one day affect who controls the land.

So the drop in the quality of sperm is raising some red flags, even though the cause remains a mystery. Speculative theories range from the mundane (carrying cellphones in front pockets) to the far-fetched (depleted uranium from exploded munitions). Some Israeli scientists are looking seriously at naturally occurring hormones, particularly estrogen, in Israel's water and milk and suggest that it's a mark of the country's aggressive dairy farming methods.

The white-coated director of the Hadassah Sperm Bank, Ruth Har-Nir, hunches over a microscope to view a freshly donated specimen and begins to methodically count each squiggly swimmer magnified on the slide.

She is checking the quality of a prospective donor, a young graduate student hoping to earn some extra cash. Though sophisticated lab machines could be used to analyze potency, Har-Nir says the old-fashioned method works best.

After a quick scan, she sits up straight and shakes her head. The number of spermatozoa darting around each tiny grid on the slide is two to four, well below the minimum six required, and nowhere near the 10 to 20 per grid that indicates the kind of healthy concentration the bank likes to see.

Also, rather than surging forward, some of the little guys flit left and right or just stall out, suggesting a weak motility.

"Under no circumstances can we accept sperm of this quality," she says. In the previous three weeks, her bank tested six candidates and rejected all. "This is the trend," she adds.

When Har-Nir helped launch the sperm bank in 1991, she says, it turned away about a third of the applicants for low quality. Using the same standard today, it would reject more than 80%. Though the bank relaxed its criteria, it still vetoes about two-thirds.

Har-Nir first noticed the problem a decade ago when she began rejecting more and more sperm from otherwise healthy young men. She shared her observations with local fertility doctors and their research has confirmed her suspicion.

Over the last 10 to 15 years, the concentration of sperm samples collected by the bank dropped 37% from 106 million cells per milliliter to 67 million, according to Dr. Ronit Haimov-Kochman, a leading Israeli infertility researcher at the Hadassah Hebrew University Medical Center.

Though declining sperm quality is an international phenomenon, the change in Israel is occurring at nearly twice the pace as other developed countries, Haimov-Kochman said. If current trends continue, she said, by 2030 the concentration of sperm from Israeli donors will drop below 20 million cells per milliliter, which many international health experts define as abnormal.

So far, there's no evidence that declining sperm quality is resulting in fewer babies. The birthrate of Israel's Jewish population has risen in recent decades, thanks largely to the increase in the number of ultra-Orthodox Jews, who tend to have large families.

Haimov-Kochman estimated that infertility rates in Israel have risen from 10% to 15% over the last 15 years, but says that's in line with international trends. But she said male infertility — once believed to be the cause about half the time, just as in the U.S. — is now suspected in 70% of the cases here.

Most worrisome, she added, is that research so far has focused on sperm-bank donors, mostly students who are younger and healthier than the general population.

"If this is happening to the guys on our A-team, we might only be seeing the tip of the iceberg," she said.

Advertisement
Los Angeles Times Articles
|
|
|