INDIANAPOLIS (5-3) AT JACKSONVILLE (1-7)
TV: NFL Network, 5:15 p.m.
Line: Colts by 3.
Sam Farmer's pick: Two teams heading in opposite directions. The Jaguars have been outscored at home, 126-34. Colts are sixth in passing, going against the NFL's worst pass defense. Colts 23, Jaguars 14.