Suppose you're under a lot of pressure. Does it feel like a huge flood is swirling around in your brain, tossing your thoughts every which way?
Well, Ashley Merryman and Po Bronson say, maybe that's because your brain really is flooded — with dopamine. Dopamine is a neurotransmitter that the brain needs to run at full capacity, but as with so many good things, it's possible to have too much of it. So, as your brain keeps producing fresh dopamine, it has to keep getting rid of the old. In the prefrontal cortex, special enzymes called COMT — for catechol-O-methyltransferase — carry out these mop-up operations.
The prefrontal cortex serves as the brain's central intelligence agency. It has to perform well for you to perform well, and it can perform well only if it has the right amount of dopamine.
But stress brings on a dopamine surge that can overwhelm your poor COMT enzymes if they don't act fast. And not everyone's can. In fact, there are two kinds of COMT enzymes, workaholics and slackers, and workaholics are four times faster.