Robert Khuzami, who revamped the Securities and Exchange Commission's enforcement division after the agency failed to stop Bernard Madoff's Ponzi scheme, is stepping down.
Khuzami, a former federal prosecutor and general counsel for Deutsche Bank, becomes the latest senior SEC official to leave as President Obama's second term gets underway.
Mary Schapiro stepped down as chairman of the agency in mid-December. The SEC lost two other major figures last month: Robert Cook, who was head of the SEC's division of trading and markets; and Meredith Cross, who was director of the agency's division of corporation finance.
The void means Chairman Elisse Walter could significantly reshape the agency by picking their replacements.
Aside from Schapiro, Khuzami was the most visible regulator after Madoff's fraud and the financial crisis that plunged the economy into turmoil.