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November 30, 2010 | By Shari Roan, Los Angeles Times
The acne drug isotretinoin, or Accutane, has been under attack for many years because of safety concerns. Reports have linked the drug to an increased risk of suicide and of inflammatory bowel disease. But in an updated position statement, the American Academy of Dermatology defends the availability of the drug and says the reports of serious side effects are not supported. The brand name drug, Accutane, is no longer manufactured. But isotretinoin is sold under a variety of other names, including Amnesteem, Claravis, Clarus and Decutan.
November 12, 2010 | By Shari Roan, Los Angeles Times
People who take the acne medication isotretinoin -- perhaps best known by the brand-name Accutane -- have a slightly higher risk of suicide than people who don't take the medication. However, the excess risk is most likely due to having severe acne, not because the drug causes psychiatric problems. Researchers from the Karolinska Institute in Sweden analyzed data from people who had taken isotretinoin from 1980 to 1989 and identified suicide attempts and deaths through 2001.
September 17, 2010
One of the problems that doomed the acne drug Accutane was a widespread perception that – along with other problems, like birth defects and inflammatory bowel disease – it made patients more prone to depression and suicide. As my colleague Shari Roan reported in a story last year explaining why drug maker Roche Holding pulled Accutane from the market : “The drug has been publicly and emotionally linked to an increased risk of depression, including suicides, and some families of suicide victims have pressed the Food and Drug Administration for its removal – among them Rep. Bart Stupak (D-Mich.
September 1, 2010 | By Bill Shaikin and E. Scott Reckard
Frank McCourt needed money last year, so he solicited an infomercial king to invest in the Dodgers. He offered an array of enticements: game tickets, preferred parking, employee discounts on team merchandise, invitations to news conferences and — atop the list of benefits — "Championship Ring (when we win World Series). " McCourt proposed a deal in which he would receive $25 million right away. He would have five years to either pay the money back, with interest, or convert the loan into a tiny share of team ownership.
February 24, 2010 | By Thomas H. Maugh II
Dr. Albert M. Kligman, a dermatologist who developed the acne drug Retin-A and the antiwrinkle cream Renova but who may be remembered primarily for a series of experiments on prisoners that led to major reforms in the U.S. medical testing establishment, died Feb. 9 at Pennsylvania Hospital in Philadelphia. He was 93. Kligman died of a heart attack, according to the University of Pennsylvania, where he had been a faculty member for 50 years. A prolific researcher, Kligman was first to describe the human hair-growth cycle, investigated the pathogenesis of acne vulgaris, identified the effects of sunlight on the skin, and coined the terms photoaging and cosmeceuticals.
December 7, 2009 | Valerie Ulene, Los Angeles Times
More than 40 percent of teens have acne that's severe enough to require treatment by a physician, according to the American Academy of Dermatology. The first line of prescription medications include topical retinoids and antibiotics. Using these drugs in combination often produces the best results, but they must be taken for as long as the acne persists, which, for some people, can be many years. Although generally well-tolerated, they frequently cause skin dryness and irritation.
December 7, 2009 | By Valerie Ulene
Overwrought at what seemed to me to be a typical smattering of pimples, my teenage daughter had been begging for months to see a dermatologist. But I'd insisted on exhausting all other approaches before going to the expense. After all, I reasoned, how hard could it be to clear up a little acne? So I proceeded to spend a small fortune on over-the-counter products that did little to improve her complexion and even sprang for a facial that left her skin looking even more angry and inflamed.
November 7, 2009 | Shari Roan
Teenagers and young adults suffering from severe, scarring acne may ultimately lose the most effective treatment for the condition. Swiss-based Roche Holding quietly pulled its blockbuster drug Accutane off the market in June amid early signs that the drug may be linked to inflammatory bowel disease. And last week, a study was released that quantified those risks, finding that users of the medication have almost twice the odds of developing a serious bowel disorder as nonusers.
November 11, 2008 | Times Staff Writer
Federico Veiroj's "Acne" won the grand jury prize and Daniel Stamm's "A Necessary Death" captured the audience award in the feature film competition at AFI Fest 2008, which concluded in Los Angeles on Sunday night. In the documentary category, Kief Davidson's "Kassim the Dream" took the grand jury prize and shared the audience award with Patrick Davidson's "The World We Want."
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