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Alzheimer S Disease

NEWS
July 23, 1994 | THOMAS H. MAUGH II, TIMES MEDICAL WRITER
People with below-average head size have as much as 18 times the normal risk of developing dementia caused by Alzheimer's and other diseases, Washington state researchers have found. The findings suggest that such individuals do not have enough brain cells in reserve to offset the loss of cells caused by aging and neurological diseases, said epidemiologist Amy B. Graves of Battelle Pacific Northwest Laboratories in Seattle.
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NEWS
July 11, 1985 | TIA GINDICK, Times Staff Writer
The facts have not gotten any more reassuring for patients of Alzheimer's disease and their families. In Los Angeles County alone, according to a study conducted in February by Westside Independent Services to the Elderly, 39,000 patients in skilled nursing homes are Alzheimer's patients. Nationally, Alzheimer's is the fourth leading cause of death behind heart disease, cancer and stroke. It affects close to 3 million Americans yearly, 20% of those older than 65.
CALIFORNIA | LOCAL
November 25, 1999
Molecular biologists have created a strain of mice that models one of the key features of Alzheimer's disease, the accumulation of "tangles" containing a protein called tau. The tangles, along with another deposit called plaque, are one of the key features of the disease, which affects as many as 4 million Americans. A team from the University of Pennsylvania reports in the November issue of Neuron that it added an extra copy of the tau gene to mice.
SCIENCE
December 10, 2005 | From Times Staff and Wire Reports
The diabetes drug Avandia can enhance memory in patients with mild Alzheimer's disease, but only in patients with a certain genetic profile, researchers from GlaxoSmithKline reported Wednesday at a UC San Diego meeting. The finding supports the hypothesis that impaired glucose metabolism may play a role in the onset of the disorder. The study, using about 500 patients, showed that the drug worked only in patients who did not have a gene variant known as ApoE4.
HEALTH
January 31, 2005 | From Reuters
People who have high blood pressure, cholesterol, diabetes or who smoke in midlife have a much higher risk of developing Alzheimer's disease later on, U.S. researchers have found. And the more factors a person has, the higher the risk. People with all four risk factors have more than double the risk of Alzheimer's, reported a team at Kaiser Permanente's division of research in Oakland. "The message is that the risk factors that are bad for the heart are bad for the brain," said Dr.
NATIONAL
September 5, 2002 | From Times Wire Reports
A government-sponsored trial aimed at seeing if painkillers can reduce the risk of Alzheimer's disease is not only useless, but dangerous and should be stopped, Public Citizen said. The consumer group, which has lobbied against certain diet pills and other drugs, said the study is using the wrong drugs.
NEWS
August 6, 1998 | DENNIS McLELLAN, TIMES STAFF WRITER
Seated in her recliner in the family room of the Long Beach duplex she shares with her identical twin, 87-year-old Ilene Eddy is reminiscing about their childhood back on the family farm in Iowa. At least she's trying to. Her twin, Irene Peterson, a few feet away in her own recliner with its matching floral chair cover, keeps interrupting. "Irene, be quiet, please!" Ilene says. "I'm trying to give information here."
CALIFORNIA | LOCAL
July 18, 1998 | DUKE HELFAND
Every Sunday morning, I play softball with a bunch of guys at Cheviot Hills Park on the Westside. As teams go, we stink, but our wives and kids always turn out for the games. A couple of Sundays ago, as we warmed up, four strangers appeared on the dugout bleachers: an elderly man and woman and two thirtysomething fellows in jeans and baseball caps. A family enjoying the park, I assumed.
NEWS
March 16, 1998 | From Times Wire Reports
Former Sen. William Proxmire, the government gadfly who handed out Golden Fleece awards to spotlight what he considered bad uses of taxpayer money, has Alzheimer's disease, the Milwaukee Journal Sentinel reported. Proxmire, 82, a Democrat who retired in 1989 after 31 years in office, told the newspaper his condition "can be called Alzheimer's disease, although I'm not as bad as that sounds." He said he reads a lot but can't go on the lecture circuit or write his newspaper column.
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