November 11, 2011 |
The decision by health experts to separate Alzheimer's disease from age-related dementia and deem it potentially curable "opened a Pandora's box" and may have misdirected research for decades, a team of scientists suggests in a new analysis of the field. Despite great efforts to find treatments to stop or slow progression of the disease, there are only a few medications for Alzheimer's disease and they only help mitigate symptoms, not the disease process. In their paper, published in the December issue of the Journal of Alzheimer's Disease , researchers from the University of South Florida propose that senile dementia, which includes Alzheimer's, is not a distinct disease but can be explained by simple aging along with other risk factors.
CALIFORNIA | LOCAL
December 26, 1988 |
Scientists using new computer technologies are gaining insight into the three-dimensional structure of some of the body's key proteins. At the forefront of this new frontier is one of these proteins--the enzyme superoxide dismutase (SOD), famous for preventing oxygen toxicity in the body and thought to hamper such diverse disorders as heart disease, cancer, Alzheimer's disease and the aging process. The scientists have already uncovered a complex scenario in which the enzyme lures and traps the superoxide molecule, which it is programmed to destroy.
July 26, 2010 |
The audience wasn't happy. Its members — private citizens, healthcare professionals and advocates for the elderly — had gathered to hear a report on how to prevent Alzheimer's; instead, they were told that, in fact, nothing has been proved to keep the disease at bay. "We're not trying to take anyone's hope away," said report co-author Dr. Carl C. Bell, a professor of psychiatry and public health at the University of Illinois, Chicago,...
November 15, 1987
The John Douglas French Center for Alzheimer's Disease, a 148-bed long-term care facility for Alzheimer's patients, will open Friday at 3957 Katella Ave., Los Alamitos. The $10-million center is the first of 12 "model-care" centers the John Douglas French Foundation for Alzheimer's Disease plans to open across the nation through joint ventures. The centers will incorporate the organization's medical care program with strict architectural design standards.
CALIFORNIA | LOCAL
November 25, 1999
Molecular biologists have created a strain of mice that models one of the key features of Alzheimer's disease, the accumulation of "tangles" containing a protein called tau. The tangles, along with another deposit called plaque, are one of the key features of the disease, which affects as many as 4 million Americans. A team from the University of Pennsylvania reports in the November issue of Neuron that it added an extra copy of the tau gene to mice.
December 10, 2005 |
The diabetes drug Avandia can enhance memory in patients with mild Alzheimer's disease, but only in patients with a certain genetic profile, researchers from GlaxoSmithKline reported Wednesday at a UC San Diego meeting. The finding supports the hypothesis that impaired glucose metabolism may play a role in the onset of the disorder. The study, using about 500 patients, showed that the drug worked only in patients who did not have a gene variant known as ApoE4.
January 31, 2005 |
People who have high blood pressure, cholesterol, diabetes or who smoke in midlife have a much higher risk of developing Alzheimer's disease later on, U.S. researchers have found. And the more factors a person has, the higher the risk. People with all four risk factors have more than double the risk of Alzheimer's, reported a team at Kaiser Permanente's division of research in Oakland. "The message is that the risk factors that are bad for the heart are bad for the brain," said Dr.
September 5, 2002 |
A government-sponsored trial aimed at seeing if painkillers can reduce the risk of Alzheimer's disease is not only useless, but dangerous and should be stopped, Public Citizen said. The consumer group, which has lobbied against certain diet pills and other drugs, said the study is using the wrong drugs.
August 6, 1998 |
Seated in her recliner in the family room of the Long Beach duplex she shares with her identical twin, 87-year-old Ilene Eddy is reminiscing about their childhood back on the family farm in Iowa. At least she's trying to. Her twin, Irene Peterson, a few feet away in her own recliner with its matching floral chair cover, keeps interrupting. "Irene, be quiet, please!" Ilene says. "I'm trying to give information here."