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Alzheimer S Disease

February 24, 1995 | TIM MAY
About 150,000 people in the Los Angeles area are afflicted with Alzheimer's disease, a dementia that can cause memory lapses and loss in mostly elderly patients, according to the national Alzheimer's Assn. "Every one of those persons is a potential wanderer," said Karen Jacobsen, director of the association's western region branch and chief of the local Safe Return program, aimed at tracking Alzheimer's patients who wander from their homes and speeding their safe return.
People with below-average head size have as much as 18 times the normal risk of developing dementia caused by Alzheimer's and other diseases, Washington state researchers have found. The findings suggest that such individuals do not have enough brain cells in reserve to offset the loss of cells caused by aging and neurological diseases, said epidemiologist Amy B. Graves of Battelle Pacific Northwest Laboratories in Seattle.
March 26, 2007 | From Times wire reports
More than 5 million Americans are living with Alzheimer's disease, a 10% increase since the last Alzheimer's Assn. estimate five years ago -- and a count that supports the long-forecast dementia epidemic as the population grays. Age is the biggest risk factor, and the report released Tuesday showed the nation is on track for skyrocketing Alzheimer's once the baby boomers start turning 65 in 2011.
August 27, 2010
A protein released when rheumatoid arthritis is present in the body may reduce the risk of Alzheimer's disease. The surprise finding in a mouse study may explain why people with rheumatoid arthritis have lower rates of developing Alzheimer's. Experts used to think that the drugs that people took for rheumatoid arthritis -- called non-steroidal anti-inflammatory drugs, or NSAIDs -- also reduced the risk of Alzheimer's disease. That led to clinical trials to see if NSAIDs reduced the risk of Alzheimer's in a range of patients.
May 27, 2008 | From Times Staff and Wire Reports
Thelma Keane, 82, the inspiration for the Mommy character in the long-running comic strip "Family Circus" created by her husband, Bil Keane, died Friday of Alzheimer's disease in Paradise Valley, Ariz. A native of Australia, she met her future husband during World War II while working as an accounting secretary. Keane was working next to her as a promotional artist for the U.S. Army. The two married in 1948 and moved to Keane's hometown of Philadelphia. They had five children and moved to the Phoenix suburb of Paradise Valley in 1958.
July 26, 2010 | By Shari Roan, Los Angeles Times
The audience wasn't happy. Its members — private citizens, healthcare professionals and advocates for the elderly — had gathered to hear a report on how to prevent Alzheimer's; instead, they were told that, in fact, nothing has been proved to keep the disease at bay. "We're not trying to take anyone's hope away," said report co-author Dr. Carl C. Bell, a professor of psychiatry and public health at the University of Illinois, Chicago,...
November 21, 2011
There's one thing that all Alzheimer's researchers agree on: The mind-robbing illness is heartbreaking. But after three decades of study that have produced neither cure nor medications that significantly slow its progress, some researchers are asking: What if it's not a disease with a cure? What if it's just an unfortunate but inevitable part of aging, along with wrinkly skin, osteoporosis and heart disease? In a study in the December issue of the Journal of Alzheimer's Disease, a research group led by Dr. Ming Chen at the University of South Florida suggests that "tremendous social pressures" have pushed scientists to target Alzheimer's as a curable disease.
November 25, 1999
Molecular biologists have created a strain of mice that models one of the key features of Alzheimer's disease, the accumulation of "tangles" containing a protein called tau. The tangles, along with another deposit called plaque, are one of the key features of the disease, which affects as many as 4 million Americans. A team from the University of Pennsylvania reports in the November issue of Neuron that it added an extra copy of the tau gene to mice.
December 10, 2005 | From Times Staff and Wire Reports
The diabetes drug Avandia can enhance memory in patients with mild Alzheimer's disease, but only in patients with a certain genetic profile, researchers from GlaxoSmithKline reported Wednesday at a UC San Diego meeting. The finding supports the hypothesis that impaired glucose metabolism may play a role in the onset of the disorder. The study, using about 500 patients, showed that the drug worked only in patients who did not have a gene variant known as ApoE4.
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