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Alzheimers Disease

The percentage of Americans over age 85 with mild or severe cases of Alzheimer's disease may be considerably higher than previously recognized, according to a study by researchers at Brigham and Women's Hospital in Boston. Alzheimer's disease is "relatively common (in people) over age 85, which is the fastest-growing age group in the United States," said Dr. Denis A. Evans, principal author of the study, published in today's Journal of the American Medical Assn.
June 21, 1987 | HARRY NELSON, Times Medical Writer
The federal government has put a promising experimental drug for Alzheimer's disease on a "fast track" toward possible licensing, a move triggered by a controversial report by a California psychiatrist in November that the drug produced dramatic improvements in a small group of patients. The government has authorized a study this summer that will involve more than 300 Alzheimer's patients at 17 medical centers throughout the country, according to Dr.
October 25, 1987 | Associated Press
Clinical studies on an experimental Alzheimer's disease drug have been halted after 20% of the test subjects experienced changes in liver chemistry, the Food and Drug Administration and the drug's manufacturer announced Saturday. FDA Commissioner Dr. Frank E. Young said the tests on the drug commonly called THA were halted through "a mutual decision" of the agency and the manufacturer, Warner-Lambert Co. of Morris Plains, N.J.
July 28, 1989 | LANIE JONES, Times Staff Writer
UC Irvine officials announced Thursday that their university and USC have received a $5-million federal grant to jointly operate a research center for Alzheimer's disease, the progressive brain disorder that affects 4 million Americans. The new center is one of 12 across the nation that were funded July 1 by the National Institute on Aging in Bethesda, Md. Others are at UC San Diego, Johns Hopkins University in Baltimore and Harvard-MIT in Boston.
February 27, 1989 | From Times Staff and Wire service reports
People with Alzheimer's disease show abnormal nerve fibers in the nose, a finding that may lead to a diagnostic test and a new avenue of research for finding a treatment, a study suggests. Nasal nerve tissue can be removed under local anesthetic, which may offer a way to study the brain disease early in its course, said researcher Barbara Talamo, director of the neurosciences program at Tufts Medical School in Boston.
November 21, 1988 | Compiled from staff and wire reports
Depression that afflicts hundreds of thousands of Alzheimer's patients may be caused by deterioration in parts of the brain that produce chemicals believed to keep people upbeat, researchers said last week. About 30% of Alzheimer's patients show depressive symptoms. To explore what might be causing their depression, Pennsylvania researchers autopsied the brains of 37 demented patients, mostly Alzheimer's victims, including 14 who were also diagnosed with major depression.
June 16, 2008 | By Kathleen Clary Miller, Special to The Times
The phone rang as I wrestled with the wood-framed window to close out the Santa Ana wind dusting the desk in my father's office. David, the hospice worker assigned to his case, wanted to know more about this 90-year-old man whose ability to speak has all but left him. Perhaps he could try to talk to him about his interests. "On the wall of his room I see a framed photograph of a sailboat -- does he know that boat?" David asks. Today, her captain's eyes are hollow and fogged in, and his 5-foot,11-inch frame weighs just 120 pounds.
February 20, 1987 | Associated Press
The genetic defect that causes an inherited form of Alzheimer's disease has been traced to the same chromosome responsible for Down's syndrome, a finding that researchers say suggests the same genes may be involved in both conditions. Scientists from Harvard Medical School and Massachusetts General Hospital, working with colleagues from other institutions, say that their results should help in isolating the culprit Alzheimer's gene and determining what goes wrong.
July 5, 1987 | THOMAS H. MAUGH II, Times Science Writer
Buoyed by their early success at treating Parkinson's disease in both animals and a small number of humans by transplanting adrenal tissues into the brain, researchers are accelerating brain graft experiments to treat diseases that involve brain degeneration. Among their immediate targets are such common disorders as Alzheimer's and Huntington's diseases, researchers said at an international meeting on brain grafting here last week.
September 19, 1989 | DAVID LARSEN, Times Staff Writer
What the three dozen experts in gerontology and mental health had in mind over the weekend was the minds of others--specifically the aging among us. And here are some of their revelations. * About 15% of Americans 65 or older who are living at home have a clinically significant degree of depression and dysphoria--persistent anxiety or physical discomfort. * Conservative estimates place the number of nursing home patients with diagnosable mental disorders at 60%.
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