CALIFORNIA | LOCAL
December 21, 2000 |
A potential Alzheimer's vaccine prevented a decline in learning and memory in mice, according to two new studies in today's Nature. The reports suggest a possibility that a vaccine can be developed to treat dementia and the loss of learning ability and memory associated with the disease in people. Tests involving humans could begin within a year.
November 27, 2012 |
A biological medication already widely used to treat plaque psoriasis may be able to slow the accumulation of amyloid plaques in the brain that are the hallmark of Alzheimer's disease, a new study has found. The same study found that in older mice with established Alzheimer's, this treatment approach, which suppresses the brain's immune reaction to beta amyloid, brought a marked improvement in cognitive function and may even halt or reverse early signs of Alzheimer's. The new study was published this week in the journal Nature Medicine.
April 15, 1991 |
An important clue to the cause of memory loss associated with Alzheimer's disease has been discovered by researchers at City of Hope in Duarte. Biochemist Eugene Roberts and his City of Hope colleagues report today in the prestigious Proceedings of the National Academy of Sciences that injections of fragments of a brain protein called beta-amyloid into the brains of mice cause the animals to forget tasks they have just learned.
CALIFORNIA | LOCAL
December 9, 1991 |
British scientists said last week that they had discovered a causal link between severe head injuries and Alzheimer's disease, a terminal brain disorder that afflicts an estimated 4 million elderly people in the United States. "It has been argued for a long time that Alzheimer's has several different causes. Our data is the first direct evidence that head injury may be one significant causative factor," said Dr. Gareth Roberts of London's St. Mary's Hospital Medical School.
January 22, 2007 |
Scientists have identified a gene that increases the risk for late-onset Alzheimer's and provides another clue into the complex mind-robbing disease. The gene -- SORL1 -- stands out because it's been tested in four ethnic groups and a form of it seems to confer a risk in all of them -- including North Europeans, Caribbean Latinos, African Americans and Israeli Arabs.
CALIFORNIA | LOCAL
July 8, 1999
Vaccination with a protein that plays a key role in Alzheimer's disease can halt progression of an Alzheimer's-like disorder in mice and may even reverse some of the symptoms, according to a report in today's Nature. The protein, called AN-1792, is a modified form of beta-amyloid peptide, one of the proteins found in the plaques and tangles in the brain characteristic of Alzheimer's disease.
October 22, 1999 |
Scientists at Amgen have isolated an elusive brain chemical believed to play a crucial role in the development of Alzheimer's disease. Reporting their findings in today's edition of Science, the researchers hope the discovery will lead to targeted treatments that can halt the advance of this mind-devouring disease that afflicts an estimated 4 million Americans.
August 19, 2013 |
New research finds that copper in amounts readily found in our drinking water, the foods we eat and the vitamin supplements we take likely plays a key role in initiating and fueling the abnormal protein build-up and brain inflammation that are hallmarks of Alzheimer's disease. While the mineral is important to healthy nerve conduction, hormone secretion and the growth of bones and connective tissue, a team of researchers from the University of Rochester Medical Center suggested that too much of it may be a bad thing, and they set about to explore copper's dark side.
September 20, 2010 |
Alzheimer's disease is a scourge of old age, robbing people of their ability to hold a thought or manage simple tasks of daily life. Once the disease takes hold, it doesn't let up, progressively worsening until death. Modern medicine has yet to discover a cure. Scientists don't even know what causes Alzheimer's and are only beginning to tease out the main risk factors for developing the disease, besides age itself. One of the leading candidates is Type 2 diabetes, in which patients stop responding properly to insulin and can't convert glucose into energy.
June 29, 2012 |
This post has been corrected. See note at the bottom for details. Who hasn't heard of mad cow disease? Maybe there are a lot more diseases like that than we recognize -- such as Parkinson's, Alzheimer's and Huntington's -- that are caused by a rogue, mis-folded piece of protein that seeds other bits of protein to mis-fold as well. So argues Stanley Prusiner, a UC San Francisco professor, in a commentary in the journal Science. Prusiner won a Nobel Prize for finding that a class of neurodegenerative diseases (of which mad cow is one)