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CALIFORNIA | LOCAL
May 14, 2013 | By Joseph Serna and Christie D'Zurilla
Angelina Jolie's decision to have a double mastectomy because of a rare gene she and relatives carry speaks to the importance of knowing your family's history with cancer, the American Cancer Society said. In an  op-ed in the New York Times  under the headline “My Medical Choice,” the Oscar-winning actress said she underwent surgical procedures to remove both breasts between February and April. Jolie, 37, said that genetic testing discovered she had the  BRCA1 gene , which increased her chances of developing breast cancer to 87%. On Tuesday, the American Cancer Society released a statement urging awareness and caution regarding testing and prophylactic surgery.
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NEWS
May 14, 2013 | By Alexandra Le Tellier
Angelina Jolie's Op-Ed in the New York Times about getting a double mastectomy after learning that she was at risk of getting breast cancer struck a chord with fellow celebs as well as with Los Angeles Times staffers Anna Gorman and Paul Whitefield , who wrote about their own experiences Tuesday.  Jolie's Op-Ed specifically focuses on BRCA1 and BRCA2, known as the breast cancer genes. “I have always told [my kids] not to worry [about me getting cancer], but the truth is I carry a 'faulty' gene, BRCA1, which sharply increases my risk of developing breast cancer and ovarian cancer ,” she writes.
ENTERTAINMENT
May 14, 2013 | By Amy Kaufman
Only moments after Angelina Jolie's revealing op-ed was published late Monday, the actress' name was trending on Twitter. From celebrities to cancer survivors, tens of thousands voiced their support for Jolie's decision to undergo a preventive double mastectomy. "I commend Angelina Jolie for her courage and thoughtfulness in sharing her story today regarding her mastectomy. So brave!" wrote Sheryl Crow, a breast cancer survivor herself. "Brave, honest strong," said Oscar winner Marlee Matlin. "Proud of her for using her incredible platform to educate women," added E!
SCIENCE
May 14, 2013 | By Amina Khan
Angelina Jolie's revelation that she underwent a preventative double mastectomy may seem like a shocking move to some. But for many women who have dangerous hereditary risks coded into their genes, this kind of surgery before cancer strikes serves as a viable alternative that's been growing in popularity over the last few decades, doctors say. For patients with a dangerous mutation in the BRCA1 or BRCA2 genes that dramatically raises their risk...
NEWS
May 14, 2013 | By Paul Whitefield
I didn't realize until now that Angelina Jolie and I have something in common: cancer. Or at least risk factors for it. Jolie, of course, has made worldwide headlines with her dramatic op-ed Tuesday in the New York Times describing her decision to undergo a double mastectomy. And clearly, family history played a big role in her choice : “My mother fought cancer for almost a decade and died at 56,” Jolie writes. “She held out long enough to meet the first of her grandchildren and to hold them in her arms.
CALIFORNIA | LOCAL
May 14, 2013 | By Joseph Serna, This post has been corrected. See note below for details.
Angelina Jolie said the decision to undergo a double mastectomy to reduce her chances of getting breast cancer "wasn't easy. " In an op-ed in the New York Times under the headline “My Medical Choice,” the Oscar-winning actress said she underwent surgical procedures to remove both breasts between February and April. Jolie, 37, said that genetic testing discovered she had the BRCA1 gene , which increased her chances of developing breast cancer to 87%. PHOTOS: Celebrities react to Jolie's double-mastectomy decision   She said she went public with her procedure to help other women.
CALIFORNIA | LOCAL
May 14, 2013 | By Los Angeles Times Staff
Angelina Jolie announced that she had a preventive double mastectomy because she had a  gene that made likely she would get breast cancer . Writing in the New York Times, Jolie, 37, said: “My mother fought cancer for almost a decade and died at 56. She held out long enough to meet the first of her grandchildren and to hold them in her arms. But my other children will never have the chance to know her and experience how loving and gracious she was. They have asked if the same could happen to me.” In 2007, Times Staff Writer Anna Gorman wrote about the drastic surgery she had after learning she had the genetic mutation, BRCA1.
CALIFORNIA | LOCAL
May 14, 2013 | By Joseph Serna
Angelina Jolie 's decision to have a double mastectomy because of a rare gene has generated great interest. But experts are urging caution regarding testing and prophylactic surgery. "This does not mean every woman needs a blood test to determine their genetic risk for breast and/or ovarian cancer ,” said Dr. Otis W. Brawley, the American Cancer Society's chief medical officer. “What it does mean is women should know their cancer family history and discuss it with their regular provider.
NEWS
May 14, 2013 | By Jon Healey
It's hard to imagine Supreme Court justices paying much attention to the travails of Hollywood's rich and famous. Still, there's an interesting connection between Angelina Jolie's disclosure Tuesday that she underwent a double mastectomy and a case the court is deliberating, the Assn. for Molecular Pathology vs. Myriad Genetics . At issue is whether a human gene sequence can be patented. That's the broad question. The two specific sequences patented by Myriad -- BRCA1 and BRCA2 -- are genes that suppress tumors . A small percentage of women have defective copies of those genes, and they are extremely likely to develop a virulent form of breast cancer.
SCIENCE
May 14, 2013 | By Amina Khan, This post has been corrected, as indicated below.
Angelina Jolie's decision to undergo a preventative double mastectomy to reduce breast cancer risk was a natural move given that she carried a dangerously faulty gene, cancer surgeons said, but it's a decision that really befits only a select group of women. Only about 5% of breast cancer patients carry a dangerous mutation in their BRCA1 or BRCA2 genes, said Dr. Julian Kim, chief of surgical oncology at the University Hospitals Case Medical Center and chief medical officer of the UH Seidman Cancer Center in Cleveland.
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