April 19, 2012 |
Researchers at San Diego's Scripps Research Institute have developed what they say could be the first effective treatment for cocaine overdoses. Their technique, which uses synthetically produced antibodies to bind cocaine and remove it from circulation, has so far been tried only in mice, but the team hopes to start human trials soon -- if they can produce enough of the antibodies in an economically viable manner. Immunologists Jennifer B. Treweek and Kim D. Janda of Scripps have in the past been working on so-called active vaccine against cocaine and nicotine.
CALIFORNIA | LOCAL
June 6, 2011 |
Physicist Rosalyn S. Yalow, who shared the 1977 Nobel Prize in Physiology or Medicine for the development of a medical diagnostic test that revolutionized patient care and led to a new understanding of diabetes and a host of other diseases, died May 30 in the Bronx, N.Y. She was 89. No cause of death was announced. Although her work in medical diagnostics was seminal, she was perhaps equally well known for her temerity in entering a field that had previously been dominated by men and for her persistence in pursuing her goals in the face of opposition from the establishment and the opposite sex. She was only the second woman to win the Nobel in medicine and only the sixth to win a Nobel in any science.
January 8, 2011 |
Construction is set to begin this month on a $95-million development in Santa Monica where a local biotech company will manufacture antibodies to fight cancer. The project, which received city approval this week, allows a consolidation and expansion of operations for Agensys Inc. The Santa Monica firm researches and develops new cancer therapies, some of which are in clinical trials. Agensys will consolidate its office, research, laboratory and manufacturing space in the development at 1800 Stewart St. on land leased from the city.
July 9, 2010 |
An effective vaccine against the AIDS virus may have moved one step closer to reality, researchers said Thursday. Federal researchers have identified a pair of naturally occurring antibodies that are able to kill more than 90% of all strains of the AIDS virus, a finding they say could lead to the development of new treatments for HIV infections and to the production of the first successful vaccine against the virus. HIV, the virus that causes AIDS, is notoriously mutable, changing the composition of proteins on its surface with ease to escape pressure from the immune system.
February 11, 2010 |
Three years after the U.S. blood-banking industry recommended against transfusing plasma from female donors because of a potentially life-threatening antibody reaction, researchers have found that plasma from women may actually be better, not worse, for heart surgery patients. In a study of patients treated before the new guidelines were implemented, those receiving plasma from women were only half as likely to suffer lung complications from the surgery and were 45% less likely to be hospitalized or die in the 10 days after surgery, a Duke University Medical Center team reported.
September 4, 2009 |
After 15 years of futile search for a vaccine against the AIDS virus, researchers are reporting the tantalizing discovery of antibodies that can prevent the virus from multiplying in the body and producing severe disease. They do not have a vaccine yet, but they may well have a road map toward the production of one. A team based at the Scripps Research Institute in La Jolla reports in Friday's journal Science that they have isolated two so-called broadly neutralizing antibodies that can block the action of many strains of HIV, the virus responsible for AIDS.