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Arthritis

CALIFORNIA | LOCAL
July 20, 1995 | From Times staff and wire reports
Adding the immunosuppressive drug cyclosporine to a regimen of the anti-arthritic drug methotrexate can significantly reduce the symptoms of rheumatoid arthritis, according to a study in the New England Journal of Medicine. A team at the University of Ottawa gave 74 arthritics methotrexate alone and 74 a combination of the two drugs. More than 48% of those who received cyclosporine showed significant improvement--less joint pain, tenderness and swelling--compared to 16% of those who received only methotrexate.
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NEWS
September 14, 1992 | GARY LIBMAN, TIMES STAFF WRITER
Elgin Baylor's first appointment with Dr. Robert Kerlan ended before it started. Waiting in Kerlan's lobby in the early 1960s, Baylor peered through a doorway and saw the orthopedist hunched over, apparently in severe pain. "He seemed to have a problem and couldn't even help himself," says the former Laker star. "I told the receptionist I was there for a cold and had come to the wrong doctor. And I left." When other doctors could not free his knees of pain, Baylor returned.
HEALTH
April 26, 2004 | Jane E. Allen
Squatting puts tremendous stress on the knees, and doing it habitually appears to contribute to arthritis later in life. To determine the extent of that risk, Boston University medical researchers studied more than 1,800 men and women age 60 and older in China, where squatting is common.
HEALTH
September 15, 1997 | THE WASHINGTON POST
Doctors know that people with osteoarthritis in their knees tend to have weak muscles around the affected joint, and exercising to strengthen those muscles has been shown to reduce pain and improve mobility. But they've generally assumed that the muscle weakness develops because pain prevents the arthritis sufferer from fully using the joint. Now a study of elderly people suggests that, at least for women, the muscle weakness may come first--or may at least develop very early in the disease.
HEALTH
August 9, 2004 | Judy Foreman, Special to The Times
Americans spend $6 billion a year on the arthritis painkillers Vioxx and Celebrex, which are said to be as good as over-the-counter drugs -- but easier on the stomach. But the two have not lived up to their hype, according to published research and interviews with arthritis doctors and drug specialists. Vioxx, which may be better for the stomach, appears to have a far worse side effect than over-the-counter drugs: an increased risk of heart attack.
NEWS
November 30, 1990 | ROBERT STEINBROOK, TIMES MEDICAL WRITER
Experiments for the first time have reproduced a form of human arthritis in genetically altered rats and confirmed a previously established link between a gene involved in regulating the immune system and this form of arthritis, researchers said Thursday. The achievement means researchers now have a reliable animal model to aid studies of ankylosing spondylitis, Reiter's syndrome, psoriatic arthritis and related diseases.
NEWS
September 12, 1998 | From Times Wire Services
Arava, a new drug for rheumatoid arthritis that helps relieve symptoms but is a far cry from a cure, won approval Friday from the Food and Drug Administration. The FDA warned that Arava is also too dangerous to use during pregnancy--bad news for many of the estimated 2 million rheumatoid arthritis sufferers in the U.S., most of whom are women.
CALIFORNIA | LOCAL
December 17, 1998 | THOMAS H. MAUGH II, TIMES MEDICAL WRITER
Allene Goodman can remember the precise day her arthritis began taking control of her life. On Aug. 3, 1987, Goodman, a medical transcriptionist, began to shiver uncontrollably, unable to warm her hands and feet. Then her feet began to swell. A trip to the nearest rheumatologist, 158 miles from her home in Caledonia, Miss., confirmed that she suffered from rheumatoid arthritis, and that day marked the beginning of a steady acceleration of her disease. The worst part, she recalls, was the pain.
SPORTS
October 18, 1993 | DAN HAFNER, TIMES STAFF WRITER
For many years, Bob Murphy was among the best at beating a golf course. Lately, he has been having the same success in a more serious matter. Murphy was forced to abandon the regular PGA Tour in January of 1989 when his arthritis became so bad he couldn't grip a golf club. But he is a glib, knowledgeable player and found a job as a TV commentator on ESPN for the senior tour. Murphy suffers from a type of arthritis known as psoriatic.
SCIENCE
September 11, 2008 | Denise Gellene, Times Staff Writer
Arthroscopic knee surgery for arthritis -- a procedure performed hundreds of thousands of times a year -- does not reduce joint pain or improve knee function, according to new research released Wednesday. The study of 178 adults with moderate to severe arthritis found that the surgery, in which damaged bone and cartilage are removed through tiny incisions, had no benefits beyond nonsurgical treatments, such as physical therapy. The report in the New England Journal of Medicine confirmed the results of a 2002 study that caused many orthopedic surgeons to discontinue the practice.
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