YOU ARE HERE: LAT HomeCollectionsArthritis


July 24, 1995 | From Times staff and wire reports
Adding the immunosuppressive drug cyclosporine to a regimen of the anti-arthritic drug methotrexate can significantly reduce the symptoms of rheumatoid arthritis, according to a study in the New England Journal of Medicine. A team at the University of Ottawa gave 74 arthritics methotrexate alone and 74 a combination of the two drugs.
Elgin Baylor's first appointment with Dr. Robert Kerlan ended before it started. Waiting in Kerlan's lobby in the early 1960s, Baylor peered through a doorway and saw the orthopedist hunched over, apparently in severe pain. "He seemed to have a problem and couldn't even help himself," says the former Laker star. "I told the receptionist I was there for a cold and had come to the wrong doctor. And I left." When other doctors could not free his knees of pain, Baylor returned.
April 26, 2004 | Jane E. Allen
Squatting puts tremendous stress on the knees, and doing it habitually appears to contribute to arthritis later in life. To determine the extent of that risk, Boston University medical researchers studied more than 1,800 men and women age 60 and older in China, where squatting is common.
September 15, 1997 | THE WASHINGTON POST
Doctors know that people with osteoarthritis in their knees tend to have weak muscles around the affected joint, and exercising to strengthen those muscles has been shown to reduce pain and improve mobility. But they've generally assumed that the muscle weakness develops because pain prevents the arthritis sufferer from fully using the joint. Now a study of elderly people suggests that, at least for women, the muscle weakness may come first--or may at least develop very early in the disease.
September 8, 2008 | Chris Woolston, Special to The Times
The products: Humans have long believed in an almost magical connection between strong flavors and good health. The burn from the hot pepper? It must be energizing the body. The pungent tang of a raw oyster? It must be energizing a very particular part of the body. And the zingy sweetness of an Indian curry? For centuries, people in India have believed that the spice turmeric can ease digestive distress and arthritis. In recent years, scientists have taken an intense interest in curcumin, a bright-yellow compound in turmeric that seems to fight inflammation -- in test tubes and lab rodents, at least.
August 9, 2004 | Judy Foreman, Special to The Times
Americans spend $6 billion a year on the arthritis painkillers Vioxx and Celebrex, which are said to be as good as over-the-counter drugs -- but easier on the stomach. But the two have not lived up to their hype, according to published research and interviews with arthritis doctors and drug specialists. Vioxx, which may be better for the stomach, appears to have a far worse side effect than over-the-counter drugs: an increased risk of heart attack.
September 11, 2008 | Denise Gellene, Times Staff Writer
Arthroscopic knee surgery for arthritis -- a procedure performed hundreds of thousands of times a year -- does not reduce joint pain or improve knee function, according to new research released Wednesday. The study of 178 adults with moderate to severe arthritis found that the surgery, in which damaged bone and cartilage are removed through tiny incisions, had no benefits beyond nonsurgical treatments, such as physical therapy. The report in the New England Journal of Medicine confirmed the results of a 2002 study that caused many orthopedic surgeons to discontinue the practice.
Experiments for the first time have reproduced a form of human arthritis in genetically altered rats and confirmed a previously established link between a gene involved in regulating the immune system and this form of arthritis, researchers said Thursday. The achievement means researchers now have a reliable animal model to aid studies of ankylosing spondylitis, Reiter's syndrome, psoriatic arthritis and related diseases.
September 12, 1998 | From Times Wire Services
Arava, a new drug for rheumatoid arthritis that helps relieve symptoms but is a far cry from a cure, won approval Friday from the Food and Drug Administration. The FDA warned that Arava is also too dangerous to use during pregnancy--bad news for many of the estimated 2 million rheumatoid arthritis sufferers in the U.S., most of whom are women.
Los Angeles Times Articles