September 5, 2008 |
Federal regulators say a drug from Pfizer Inc. and Ligand Pharmaceuticals Inc. effectively treats osteoporosis, but they are concerned about deaths, blood clots and other problems seen in company studies. The Food and Drug Administration noted that women treated with Pfizer's Fablyn were more likely to die of cancer or stroke than those taking a placebo. The FDA posted its review of the drug online in advance of a meeting Monday with outside advisors.
CALIFORNIA | LOCAL
December 13, 2007 |
A Catalina Island woman was acquitted Wednesday of murdering her newborn daughter and stuffing the body into a trash container, in the second rebuff this month to Los Angeles County prosecutors seeking criminal convictions for baby dumping. Leticia Castro sobbed loudly and thanked the jury for its decision in the 2004 case, said Jay Glaser, her attorney.
October 6, 2007 |
Isaac Hanson, the frontman of pop group Hanson, left a Dallas hospital Friday after doctors removed a blood clot that caused his right arm to painfully swell during a concert this week. Hanson, 26, underwent surgery Thursday for venous thoracic outlet syndrome, which doctors said interrupted the blood flow from his arm back to his heart. Dr. Bradley Grimsley, who performed the surgery, expects Hanson to make a full recovery. Isaac Hanson performs with his brothers, Taylor, 24, and Zac, 21.
July 30, 2007 |
BLOOD clots can be painful, difficult to diagnose, even life-threatening. But hospital patients -- who are at an especially high risk of developing the condition -- often don't receive treatment to prevent them, researchers have found. A hospital stay, even one as short as a few days, can greatly increase the chance of developing a clot in the legs or lungs. In fact, blood clots in the lungs, known as pulmonary embolisms, are blamed for as much as 10% of deaths in hospitalized patients.
July 23, 2007 |
Two drugs are not always better than one when it comes to using blood thinners to treat clogged arteries in the legs, U.S. researchers have reported. They found that adding a blood thinner such as warfarin to daily clot-preventing drugs such as aspirin is no better -- and sometimes more dangerous -- for preventing heart attacks, strokes and other circulatory problems in people with peripheral artery disease. About 1 in 16 people over 40 -- 8.
March 6, 2007 |
Vice President Dick Cheney is being treated for a blood clot in his left leg, his office announced Monday -- a condition that, if left untreated, can be deadly if the clot breaks loose and reaches the heart, brain or lungs. The vice president, who has had four heart attacks and experienced other cardiovascular problems over the last three decades, is being treated with blood-thinning medication, said his deputy press secretary, Megan McGinn.
January 21, 2007 |
Personalized medicine, the tailored treatments that a few patients get based on their own DNA, is finally headed for the masses: the many heart patients at risk of deadly blood clots. At least 2 million Americans with an abnormal, clot-triggering heart rhythm take the pill warfarin, also sold as Coumadin. Getting too little can lead to a stroke, and too much can cause life-threatening bleeding.
December 6, 2006 |
Patients who have received a drug-coated stent to prop open an artery face double the risk of heart attack or death after they stop taking an anti-clotting drug, researchers said Tuesday. The findings mean patients may need to stay on medication beyond the three to six months currently recommended and possibly for the rest of their lives, scientists said.
November 30, 2006 |
Two senators called on the Pentagon on Wednesday to investigate the military's use of a largely experimental blood-coagulating drug that doctors inject into wounded troops to control bleeding, but which has been linked to unexpected and potentially deadly blood clots. Sen. Barbara A. Mikulski (D-Md.) sent a letter to Dr. William Winkenwerder Jr., assistant secretary of Defense for health affairs, asking him to launch an investigation into use of the drug, called Recombinant Activated Factor VII.
November 24, 2006 |
American military doctors in Iraq have injected more than 1,000 wounded troops with a potent and largely experimental blood-coagulating drug despite mounting medical evidence linking it to deadly blood clots that lodge in the lungs, heart and brain. The drug, called Recombinant Activated Factor VII, is approved in the U.S. for treating only rare forms of hemophilia that affect about 2,700 Americans.