SCIENCE
August 28, 2012 | By Thomas H. Maugh II, Los Angeles Times
Since tissue plasminogen activator (tPA) was approved by the Food and Drug Administration in 1996 for the dissolution of blood clots in the brain that cause strokes, it has been the primary treatment for stroke victims. But it has several limitations. In most cases, it must be used within three hours after the stroke to be effective, although in some cases the crucial window can be extended to 4.5 hours. It is also often not effective in dissolving larger blood clots. On 2004, the FDA approved the first mechanical system for removing clots from the brain, the Merci Retrieval System.
SCIENCE
July 2, 2012 | By Jon Bardin, Los Angeles Times / For the Science Now blog
It's the most exciting use of the 3-D printer since the burritoBot : Scientists have figured out a way to make networks of blood vessels out of sugar that can be surrounded by living cells, bypassing what had been a major roadblock in the path to creating organs for transplant, or even lab-made prime steaks. Researchers have made significant progress toward the production of living tissue in the lab, but the studies have been plagued by an inability to successfully fill the tissues with vasculature.
SCIENCE
June 20, 2012 | By Thomas H. Maugh II
Lucentis, known generically as ranibizumab, is the only drug approved by the Food and Drug Administration for treating the wet form of age-related macular degeneration, commonly known as AMD. But Lucentis costs as much as $2,000 per dose, so many physicians have begun substituting the similar anti-cancer drug Avastin (bevacizumab), which costs less than $150 per dose. Some studies have indicated that Avastin is just as effective as Lucentis, and many public agencies in the United States and Canada have begun authorizing its use in an effort to save money, although such use has not been approved by the FDA or its Canadian equivalent.
NATIONAL
June 19, 2012 | By Laura J. Nelson
With the help of power tools and industrial-grade vise grips, Miami doctors have successfully removed a 3-foot spear that pierced a teenager's skull during a fishing accident. And Tuesday, 16-year-old Yasser Lopez left the intensive care unit. “It could be a complete recovery,” said Dr. Ross Bullock, a neurosurgeon at the University of Miami-Jackson Memorial Hospital. “That is so rare.” The afternoon of June 7, Lopez's 15-year-old friend misfired a Cressi Sub SL spear gun while trying to load it, according to the Miami-Dade Police Department.
HEALTH
March 21, 2012 | By Eryn Brown, Los Angeles Times
Doctors are one step closer to a simple test that could predict whether a patient is about to have a heart attack - by using a blood sample to detect cells that have sloughed off of damaged blood vessel walls. The finding, published Wednesday in the journal Science Translational Medicine, could potentially address "the greatest unmet need" facing cardiologists, said lead author Dr. Eric Topol, a cardiologist at the Scripps Translational Science Institute in San Diego. Though physicians can easily detect a heart attack that's already underway, every year tens of thousands of patients walk away from the doctor's office after having passed a stress test, only to suffer a devastating heart attack within a few weeks.
NEWS
February 20, 2012 | By Amina Khan, Los Angeles Times / For the Booster Shots blog
British actress Judi Dench is seeking to downplay fears over the revelation that she is suffering from a degenerative eye condition. The Oscar-winning Dench, perhaps best known as James Bond's mysterious boss M, has been dealing with two different forms of macular generation -- one in each eye. According to Reuters, she can no longer read scripts and has to have someone read them out loud to her, "like reading me a story. " According to the National Eye Institute, macular degeneration occurs in an area known as the macula, which sits at the center of the light-sensitive tissue known as the retina, located at the back of the eye socket.