CALIFORNIA | LOCAL
October 23, 2012 |
E. Donnall Thomas, a physician who pioneered the use of bone marrow transplants in leukemia patients and won the 1990 Nobel Prize in medicine, died Saturday in Seattle of heart disease. He was 92. The Fred Hutchinson Cancer Research Center in Seattle, which Thomas joined in 1974, announced his death. Thomas' work is among the greatest success stories in the treatment of cancer. Bone marrow transplantation and its sister therapy, blood stem cell transplantation, have improved the survival rates for patients with some blood cancers to around 90% from almost zero.
CALIFORNIA | LOCAL
May 2, 2012 |
Episcopal Bishop J. Jon Bruno, head of the six-county Los Angeles diocese, has been diagnosed with leukemia and is undergoing aggressive treatment to fight the disease. The 65-year-old bishop said in an open letter that he had been suffering from what he thought was a bout of pneumonia since March. He underwent further tests after treatment failed to cure the "nagging problem. " Doctors at Good Samaritan Hospital discovered that Bruno had acute monocytic leukemia, a form of blood cancer.
August 11, 2011 |
In a potential breakthrough in cancer research, scientists at the University of Pennsylvania have genetically engineered patients' T cells — a type of white blood cell — to attack cancer cells in advanced cases of a common type of leukemia. Two of the three patients who received doses of the designer T cells in a clinical trial have remained cancer-free for more than a year, the researchers said. Experts not connected with the trial said the feat was important because it suggested that T cells could be tweaked to kill a range of cancers, including ones of the blood, breast and colon.
June 5, 2011 |
To many of the nation's million people living with a diagnosis of HIV/AIDS, Timothy Brown is the Harry Potter of the disease: Like the young wizard who survived Lord Voldemort's wrath, he is the boy who lived. Today, almost 20 years after he became infected, Brown is, essentially, cured. Brown, now 45, is known in medical-journal circles as "The Berlin Patient," a moniker assigned him by a February 2009 case study published in the New England Journal of Medicine. In a "Brief Report," oncologist Gero Huetter and his colleagues at Berlin's University Hospital described the unique stem-cell transplant of an HIV-infected patient — Brown — who had acute myeloid leukemia, and the remarkable result: Twenty months after the procedure, the virus had not reappeared in Brown's body, even though he was no longer taking antiretroviral drugs.
CALIFORNIA | LOCAL
February 5, 2011 |
Dr. Ernest McCulloch, who with biophysicist James E. Till was the first to isolate and identify a stem cell, opening the door immediately to bone marrow transplants and eventually to what researchers believe will be a host of treatments for a broad spectrum of diseases ranging from spinal cord injuries to Alzheimer's, died Jan. 20 in Toronto, just two weeks shy of the 50th anniversary of the publication of the pair's seminal discovery. He was 84. "It's impossible to overstate the enormity of Till's and McCulloch's discovery and longtime collaboration," Dr. Christopher Paige of the Ontario Cancer Institute, where the pair worked, said in a statement.
August 21, 2010 |
Clad in a yellow gown, blue foot covers, hair net, face mask and latex gloves, Paula Cannon pushed open the door to the animal room. "I hate this smell," she said, wrinkling her nose. The stink came from scores of little white mice scurrying about in cages. Some of the cages were marked with red biohazard signs, indicating mice that had been injected with HIV. Yet, in some of the animals — ones with a small genetic change — the virus never took hold. Like mouse, like man?