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CALIFORNIA | LOCAL
December 19, 2008 | Scott Glover
Patients of a West Hollywood dermatologist became unwitting guinea pigs for an experimental drug when the doctor began secretly injecting them with an unapproved substitute for Botox, federal authorities allege. Dr. David Cary Hansen was indicted Wednesday by a federal grand jury in Los Angeles in connection with an alleged scheme to treat patients with an experimental form of the popular wrinkle reducer that was labeled "Not for Human Use."
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BUSINESS
September 12, 2008 | From the Associated Press
Botox, the botulism-based drug that has wiped wrinkles from the faces of millions, may be approved for another use: stopping headaches. Drug maker Allergan Inc. said Thursday that it had new evidence that its injectable drug could help relieve migraine headaches. Based on preliminary results from two company-funded studies, Allergan said it would ask the Food and Drug Administration to approve Botox for chronic migraine next year. The FDA approved Botox to smooth wrinkles and age lines in 2002, and it has grown into a blockbuster product for Irvine-based Allergan, with $2.1 billion in sales last year.
BUSINESS
July 31, 2008 | From Times Wire Services
Allergan Inc., maker of the wrinkle smoother Botox, said second-quarter profit rose 6.9% as overseas sales of facial treatments and prescription eye-care products helped the Irvine company weather a slowing U.S. economy. Net income increased to $147.3 million, or 48 cents a share, from $137.8 million, or 45 cents, a year earlier. Adjusted profit of 63 cents a share matched analysts' estimates. Revenue climbed 20% to $1.17 billion, topping the average estimate of $1.14 billion in a Bloomberg survey.
BUSINESS
July 10, 2008 | Lisa Girion, Times Staff Writer
More than a dozen Botox users and relatives filed a lawsuit Wednesday contending that the blockbuster wrinkle-buster injured them or killed their relatives, and they blamed maker Allergan Inc. for failing to warn them of the dangers. The suit, filed in Orange County Superior Court near Allergan's Irvine headquarters, links the toxin-based drug to three deaths, including one in March of a 69-year-old Texas nurse who received injections for neck and shoulder pain.
HEALTH
May 12, 2008 | Jill U. Adams, Special to The Times
Growing older has its perks -- heftier income, respect of one's peers -- and its drawbacks such as, for men, a steady enlargement of the prostate gland. Soon, men with this problem may have a broader set of therapeutic options. A 2003 study already has revolutionized the standard of care men get for this common condition.
BUSINESS
May 8, 2008 | From Times Wire Services
Allergan Inc.'s net income more than doubled in the first quarter as sales accelerated outside the U.S. for the wrinkle remover Botox. Demand cooled in the U.S., and the company blamed the economy. Net income increased to $111.4 million, or 36 cents a share, from $43.8 million, or 14 cents, a year earlier, the company said. Revenue grew 23% to $1.08 billion, bolstered by converting overseas sales in other currencies to the dollar. Irvine-based Allergan sells cosmetic and medical products including breast implants, surgical devices to remedy obesity and a treatment for overactive bladders.
ENTERTAINMENT
April 13, 2008 | Mary McNamara, Times Television Critic
I know we're all supposed to be watching this season of "Dancing With the Stars" to see whether professional athletics or Broadway provides a better foundation for dance. But I'm pretty sure most of us are far too preoccupied with figuring out whether Priscilla Presley has had the first successful head transplant and why there wasn't a "Frontline" or at least an E! special about it.
AUTOS
March 26, 2008 | DAN NEIL
I would like to give my Nissan Murano test vehicle an Advil, or Tylenol, or perhaps I should Simoniz its hood with that HeadOn stuff that you apply directly to the forehead. This thing looks like it's suffering from the world's worst migraine. To signal, I suppose, the model-year face-lift, Nissan designers gave the 2009 Murano a tensed chrome brow, a fierce furrowing that is, actually, quite a bit more aggressive than anything else in the Nissan garage.
BUSINESS
March 5, 2008 | Lisa Girion, Times Staff Writer
The U.S. Department of Justice is looking at Allergan Inc.'s promotion of its blockbuster wrinkle drug Botox for medical uses, but investors didn't seem too worried about the news Tuesday. Allergan shares closed at $57.38, down $1.28 or 2.2% on word that the Irvine company received a subpoena from the U.S. Attorney's Office for the Northern District of Georgia demanding documents regarding its promotional and educational practices involving the use of the botulinum toxin-based drug for medical problems.
BUSINESS
February 9, 2008 | By Lisa Girion, Los Angeles Times Staff Writer
Concerns about the widely used anti-wrinkle treatment Botox and a similar drug arose Friday as federal regulators said they were reviewing reports of at least one death and other serious reactions among some patients. Food and Drug Administration officials said they were not aware of any deaths among cosmetic users of Botox, the trade name for the blockbuster wrinkle buster made by Irvine's Allergan Inc. The FDA said it had reports of at least one death among patients who received a botulinum-based drug and what one official described as a "a relative handful" of serious side effects in which the toxin spread beyond the injection site.
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