CALIFORNIA | LOCAL
January 5, 2013 |
Elwood Jensen, a medical researcher whose ground-breaking work in the field of endocrinology and breast cancer led to revolutionary and life-saving treatments, died of complications from pneumonia on Dec. 16 in suburban Cincinnati, the University of Cincinnati announced. He was 92. He was repeatedly nominated for the Nobel Prize for his discovery of hormone receptors while at the University of Chicago in the 1950s and 1960s. At Chicago, Jensen focused on the impact that breast tissue had on estrogen while most other researchers analyzed how the hormone influenced tissue.
May 30, 2012 |
When cancer blooms in the body, tiny bits of tumor DNA can be found in the blood . Cancer specialists would love it if these DNA fragments could one day be used in noninvasive diagnostic tests -- “liquid biopsies ” -- that are relatively inexpensive and sensitive. There's a lot of work going on in this area right now. One team of researchers reported a step toward that goal in a paper published Wednesday in the journal Science Translational Medicine.
January 31, 2012 |
Exercise has been touted as a good way to help prevent certain diseases and conditions, but can it be useful after the fact? Yes, says a study, which suggests that a fitness regimen can enhance the health of patients following treatment. The paper analyzed 34 studies that looked at the effect of exercise on patients who had breast cancer, as well as other types of cancer, such as prostate and lung. The various studies included aerobic, resistance and strength workouts, the average length was 13 weeks and the average number of people in each trial was 93. Most of the control groups consisted of people who were sedentary or told to do no exercise.
January 9, 2012 |
Chemotherapy can destroy ovarian function in premenopausal women and much research has been dedicated to finding ways to preserve fertility in these women. Among breast cancer patients, for instance, about one in 200 are younger than age 40, and some of them may wish to become pregnant after successful cancer treatment. At least one of the strategies to preserve fertility in these women looks to be a failure, however. Researchers led by Dr. Pamela Munster at UC San Francisco conducted a study of premenopausal women undergoing chemotherapy.
December 7, 2011 |
The FDA last month rescinded approval for Avastin to treat advanced breast cancer because although preliminary studies show it led to longer periods of disease-free survival it did not increase overall survival. But a study presented Wednesday suggests their may be a role for Avastin after all. The phase-3 study was conducted among 424 women a type of breast called HER-2 positive disease. A new analysis of the data, presented at the San Antonio Breast Cancer Symposium found that adding Avastin to a regimen of Herceptin and docetaxel resulted in a 28% reduced rate of disease progression or death.
November 18, 2011 |
The cancer drug Avastin should not be used to treat breast cancer that has spread to other organs because it doesn't help patients enough to justify its risky side effects, the Food and Drug Administration ruled Friday. The decision comes five months after an FDA advisory committee recommended that the federal agency withdraw its approval of Avastin for breast cancer patients. Clinical trial results have fueled doubts for years about its value for treating breast cancer. Still, FDA Commissioner Margaret A. Hamburg said the choice was difficult because so many women and their doctors have put their faith in the drug and lobbied hard on its behalf.