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Cardiovascular Disease

HEALTH
April 5, 2010 | By Kendall Powell, Special to the Los Angeles Times
The differences in men and women's hearts may not be limited to problems of the small and large arteries. Sudden cardiac arrest and how it's predicted may play out differently by gender as well. In the U.S., sudden cardiac arrest claims around 250,000 lives each year, which is about 30% of the total deaths from cardiovascular disease. In sudden cardiac arrest, the heart's electrical activity becomes disrupted or chaotic, preventing the organ from beating. Without immediate treatment by an external defibrillator or cardiopulmonary resuscitation, the victim will die; the mortality rate is 95%. In a heart attack, blood flow to the heart muscle is restricted, causing damage to the muscle.
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SCIENCE
March 11, 2013 | By Eryn Brown, Los Angeles Times
People tend to think of heart disease as a scourge of modern life, brought on by vices such as greasy fast food, smoking and the tendency to be a couch potato. But 21st century CT scans of 137 antique mummies gathered from three continents show that hardened arteries have probably plagued mankind for thousands of years - even in places like the Aleutian Islands, where hunter-gatherers subsisted on a heart-healthy marine diet and occasional snacks of berries. Fully a third of the mummies examined - who lived in the American Southwest and Alaska as well as Egypt and Peru as much as 5,000 years ago - appeared to have the same vascular blockages that cause heart attacks and strokes in Americans today.
NEWS
October 17, 2012 | By Mary MacVean
African American adults who were counseled to eat more produce and get more exercise as ways to reduce their chances of getting cancer and heart disease ate more fruit over the course of a month, researchers said. But they didn't exercise or up their consumption of vegetables, according to the work presented Wednesday at the American Assn. for Cancer Research meeting in Anaheim. The work was looking at the notion that a greater effect could be achieved if people understood that one risky behavior - a poor diet, for instance - is associated with the chance of developing multiple diseases, said Melanie Jefferson of the Medical University of South Carolina, the lead researcher.
NEWS
June 4, 2013 | By Mary MacVean
It's no surprise that someone who has never smoked, who eats a Mediterranean diet and keeps a normal weight and who exercises regularly is healthy. How healthy? Chances of death from all causes is reduced by 80% over eight years. Pretty healthy. Those four healthy behaviors also protected against heart disease and the buildup of calcium deposits in the arteries, the researchers said. Those are the results of a multiyear study of more than 6,000 people led by Johns Hopkins University researchers and published online Monday in the American Journal of Epidemiology.
SCIENCE
November 6, 2012 | By Amina Khan, Los Angeles Times
Black men and women are twice as likely to die from coronary heart disease as white men and women, according to a study led by University of Alabama doctors. Death rates from heart attacks and coronary heart disease have fallen since the 1970s, but that statement rings far truer for whites than for blacks. Studies have shown a widening gap between whites and blacks in heart disease deaths and in heart-attack hospitalizations, and new research pins down just how deadly that difference is. A paper published in this week's Journal of the American Medical Assn.
NEWS
May 18, 1994 | STEVE EMMONS
The prognosis for Alzheimer's patients nowadays is still not good. Cognex, the one drug approved to treat the condition, only relieves symptoms. But, according to Carl W. Cotman, a prominent psychobiologist who directs UC Irvine's research into Alzheimer's, efforts toward understanding the disease "are going like gangbusters. It's an amazing rate of progress." Drugs that may slow the disease are being tested.
NEWS
January 14, 2001 | JEFF DONN, ASSOCIATED PRESS
Paul W. Ewald's best thinking started with an attack of diarrhea on a field trip to Kansas. A zoologist, he was studying the social habits of sparrows. But during that ordeal 24 years ago, he had time to ponder other things: Was his personal predicament simply the havoc of a germ bent on spreading itself around? Or was his body trying to flush away the germ? Was this the evolutionary adaptation of an invader or the evolved human defense against it?
FOOD
November 3, 1988 | TONI TIPTON
Here is a glossary of terms frequently used in discussions of cardiovascular disease and risk factors for that illness. Also included are definitions for a variety of the fiber foods often mentioned in relation to this disease and its prevention. Atherosclerosis: A disease that begins early in life with the formation of cholesterol-containing plaque or fatty streaks on the inner walls of the arteries, eventually narrowing them and inhibiting blood flow.
CALIFORNIA | LOCAL
November 23, 1995 | From Times staff reports
Scientists have linked cardiovascular disease to an age-related breakdown of telomeres, repetitive strings of DNA on the ends of chromosomes. Every time a cell divides, a bit of the telomere is lost. Ultimately, when all the telomere is gone, the cells are unable to divide. Previous research has shown that cancer cells are able to prevent the telomeres from being shortened, and are thus able to continue dividing indefinitely. A team from Geron Corp. reports in the Proceedings of the National Academy of Sciences that blood vessel cells involved in atherosclerosis have shortened telomeres, suggesting that they have prematurely aged for an as-yet-unknown reason.
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