March 4, 2011 |
The anti-epilepsy drug topiramate triples the risk of cleft palate and other birth defects of the oral cavity when taken during the first trimester of pregnancy compared with other anti-epilepsy drugs, the Food and Drug Administration warned Friday. In addition to being used to control epileptic seizures, the drug, sold under the brand name Topamax, is FDA-approved for preventing migraine headaches and is used off-label for some other purposes, including appetite control. For those uses, the risk is much higher.
CALIFORNIA | LOCAL
April 1, 2010 |
On a rainy afternoon in a cramped trailer, the five homemakers listened as state officials with clipboards asked personal questions: Did they or their husbands smoke, drink or take illicit drugs? Had they been exposed to pesticides or other toxic substances in the United States or Mexico? Do their families have histories of birth defects? Each had miscarried a fetus or given birth to a child with severe birth defects within the last three years. Each suspected it had something to do with a nearby toxic waste facility.
February 17, 2010 |
Archaeologists have weaved elaborate tales of intrigue and deceit about the death at age 19 of Egypt's fabled boy king Tutankhamen, with theories that include poisoning by his regent, Aye, and a blow to the head by thugs hired by Aye, but new research indicates his cause of death was probably more mundane -- complications from a broken leg and malaria. Using a new approach for analyzing mummies called molecular Egyptology, an international team of researchers found DNA traces of malaria parasites in the boy-king's brain, suggesting an infection was a major factor in his death.
May 21, 2007
Re: "Anesthesia: A Medical Mainstay Re-examined" [May 14], thank you for publishing this article. In general, this report was accurate, emphasizing our continuing commitment to advancing the science of anesthesiology and the comfort and well-being of those for whom we care. It is imperative to point out several caveats to the research in the article. The exposure of laboratory animals to anesthetic agents is very different than the administration of surgical anesthesia to patients.
CALIFORNIA | LOCAL
September 1, 2002 |
Dr. Janusz Bardach, 83, a Polish immigrant who spent five years in a Siberian prison camp and later became one of the most respected plastic surgeons in the world, died Aug. 16 in Iowa City, Iowa, of pancreatic cancer. He pioneered the Bardach palatoplasty, a surgical technique for repairing cleft lips and palates that reduced the number of required surgeries, improved speech and reduced scarring.
July 9, 1997 |
You'd think a baby born with only one ear would be entitled to surgery that fixes the problem. Forget about it. In the confusing world of what some doctors call "mangled care," the outer ear is often considered irrelevant. Listen to Barbara Scarlett, office manager for Berkeley plastic surgeon Michael Cedars: "I tell the insurer that this little guy was born minus an ear and we're going to fix it. The insurer says he can hear without the ear, so why bother?