August 26, 2010
An experimental anticancer drug that targets a specific genetic mutation benefits 80% of patients with metastatic melanoma, although in some cases the benefit was short-lived, researchers said Wednesday. The results came in a relatively small Phase II clinical trial, and testing will now proceed to a larger Phase III trial to gain approval for marketing the drug, called PLX4032. Researchers hope the drug might also provide benefits for some other types of tumors that share the same genetic defect.
May 11, 2010 |
Reporting from Chicago After decades of research and multiple failed attempts to find a treatment, the pharmaceutical industry is entering a crucial phase in the search for a drug that can slow, or stop, the progression of Alzheimer's disease. Drug makers see huge moneymaking potential because of the aging population. Alzheimer's afflicts more than 5 million Americans and is one of the leading causes of death in the United States, according to the Centers for Disease Control and Prevention.
January 1, 2001 |
Drug companies have pills aplenty in the pipeline, but they won't make it to market until they've been tested on humans. Finding the right patients for trials of new drugs is a costly headache, though, for pharmaceutical firms and for the federal government, which also sponsors experimental trials. Meanwhile, for people who are seriously ill, the appropriate trial can mean a shot at a new treatment that might help. This could be a job for . . . the Internet.
CALIFORNIA | LOCAL
August 22, 2006 |
The National Institutes of Health have reopened an inquiry into the activities of two UC Irvine psychiatrists in the wake of a report in The Times that they skirted the school's patient safety review board to test a drug without permission from the university. The NIH, the primary government agency for funding of medical research, previously had looked into the drug company test by Steven G. Potkin and William E. "Biff" Bunney in 2005 after it received an anonymous complaint.
November 21, 2005
Chromium is an essential trace mineral found in a variety of foods, including whole grains, cereals, spices (such as black pepper), broccoli, mushrooms, cheese, seafood and meat. In the body, it plays a role in metabolizing fats and carbohydrates and controlling blood levels of sugar. The body has a hard time absorbing chromium supplements in mineral form; it is absorbed more easily when it's bound to another molecule.
July 16, 1995
Isis Pharmaceuticals was pleased to be included in the "Biotech Blues" (July 9) article depicting the challenges biotechnology faces in raising the necessary capital to fund research and development. We would like to correct some information that was referenced in the article concerning the timing of clinical trials for two of the company's compounds. The drug discovery and development process is a high-risk venture, and it is difficult to predict the timelines for when compounds will move from one phase of clinical testing to another, and for when each of those phases will be completed.