SCIENCE
May 24, 2005 | Thomas H. Maugh II, Times Staff Writer
The widely used cholesterol-lowering drug Crestor has at least twice the incidence of side effects as other drugs in the statin family, although it should still be considered safe for long-term use, according to a study released Monday. The findings suggest that Crestor, manufactured by AstraZeneca, should probably be reserved for patients who have had a hard time lowering their overall cholesterol levels with other statins, said Dr. Richard H.
NATIONAL
March 3, 2005 | Ricardo Alonso-Zaldivar, Times Staff Writer
The Food and Drug Administration urged doctors Wednesday to use caution in prescribing the cholesterol drug Crestor to patients of Asian heritage, but said that overall the medication carried no higher risk of serious side effects than its competitors. Issuing a public health advisory and changes to prescribing information for doctors, the agency said that Asian patients should be started at the lowest approved dose, 5 milligrams a day.
SCIENCE
November 10, 2008 | Thomas H. Maugh II, Maugh is a Times staff writer.
In results from an eagerly anticipated study that could dramatically change the treatment of cardiovascular disease, researchers have found that statin drugs -- now given to millions of people with high cholesterol -- can halve the risk of heart attacks and stroke in seemingly healthy patients as well.
SCIENCE
November 20, 2004
Accutane Potent acne drug tied to severe birth defects Accutane is a highly effective drug for clearing up severe acne that is resistant to other forms of treatment. Derived from vitamin A, it essentially stops the production of oil in the sebaceous glands of the skin, shrinking those glands to the size of a baby's. The drug causes dry lips in most patients, dry eyes (which can lead to conjunctivitis) in 40% of patients, and back pain in 30% of patients.