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Crestor Drug

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June 7, 2005 | From Times Wire Reports
AstraZeneca's Crestor cholesterol drug may have triggered a temporary weakening in a 67-year-old woman's heart, Mayo Clinic doctors said in a letter published in the Annals of Internal Medicine. Kidney and muscle complications from Crestor may have caused the woman's heart to pump about a fifth as much blood as normal on each beat, James Ireland, a Mayo Clinic doctor, said in Rochester. He was one of four authors of the letter, published under the heading "Clinical Observation."
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SCIENCE
March 14, 2006 | Denise Gellene, Times Staff Writer
Intensive doses of a cholesterol-lowering statin drug have for the first time cleared sticky plaque lodged in arteries, opening the possibility of a nonsurgical method of treating the major cause of heart attacks, researchers reported Monday. The results were seen in a study of 500 patients taking the highest recommended dosage of Crestor -- 40 milligrams -- quadruple the typical starting dose of 10 milligrams.
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SCIENCE
March 14, 2006 | Denise Gellene, Times Staff Writer
Intensive doses of a cholesterol-lowering statin drug have for the first time cleared sticky plaque lodged in arteries, opening the possibility of a nonsurgical method of treating the major cause of heart attacks, researchers reported Monday. The results were seen in a study of 500 patients taking the highest recommended dosage of Crestor -- 40 milligrams -- quadruple the typical starting dose of 10 milligrams.
NATIONAL
June 7, 2005 | From Times Wire Reports
AstraZeneca's Crestor cholesterol drug may have triggered a temporary weakening in a 67-year-old woman's heart, Mayo Clinic doctors said in a letter published in the Annals of Internal Medicine. Kidney and muscle complications from Crestor may have caused the woman's heart to pump about a fifth as much blood as normal on each beat, James Ireland, a Mayo Clinic doctor, said in Rochester. He was one of four authors of the letter, published under the heading "Clinical Observation."
SCIENCE
May 24, 2005 | Thomas H. Maugh II, Times Staff Writer
The widely used cholesterol-lowering drug Crestor has at least twice the incidence of side effects as other drugs in the statin family, although it should still be considered safe for long-term use, according to a study released Monday. The findings suggest that Crestor, manufactured by AstraZeneca, should probably be reserved for patients who have had a hard time lowering their overall cholesterol levels with other statins, said Dr. Richard H.
NATIONAL
March 3, 2005 | Ricardo Alonso-Zaldivar, Times Staff Writer
The Food and Drug Administration urged doctors Wednesday to use caution in prescribing the cholesterol drug Crestor to patients of Asian heritage, but said that overall the medication carried no higher risk of serious side effects than its competitors. Issuing a public health advisory and changes to prescribing information for doctors, the agency said that Asian patients should be started at the lowest approved dose, 5 milligrams a day.
SCIENCE
November 10, 2008 | Thomas H. Maugh II, Maugh is a Times staff writer.
In results from an eagerly anticipated study that could dramatically change the treatment of cardiovascular disease, researchers have found that statin drugs -- now given to millions of people with high cholesterol -- can halve the risk of heart attacks and stroke in seemingly healthy patients as well.
SCIENCE
November 20, 2004
Accutane Potent acne drug tied to severe birth defects Accutane is a highly effective drug for clearing up severe acne that is resistant to other forms of treatment. Derived from vitamin A, it essentially stops the production of oil in the sebaceous glands of the skin, shrinking those glands to the size of a baby's. The drug causes dry lips in most patients, dry eyes (which can lead to conjunctivitis) in 40% of patients, and back pain in 30% of patients.
SCIENCE
May 24, 2005 | Thomas H. Maugh II, Times Staff Writer
The widely used cholesterol-lowering drug Crestor has at least twice the incidence of side effects as other drugs in the statin family, although it should still be considered safe for long-term use, according to a study released Monday. The findings suggest that Crestor, manufactured by AstraZeneca, should probably be reserved for patients who have had a hard time lowering their overall cholesterol levels with other statins, said Dr. Richard H.
NATIONAL
March 3, 2005 | Ricardo Alonso-Zaldivar, Times Staff Writer
The Food and Drug Administration urged doctors Wednesday to use caution in prescribing the cholesterol drug Crestor to patients of Asian heritage, but said that overall the medication carried no higher risk of serious side effects than its competitors. Issuing a public health advisory and changes to prescribing information for doctors, the agency said that Asian patients should be started at the lowest approved dose, 5 milligrams a day.
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