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Cystic Fibrosis

SCIENCE
September 18, 2010 | By Karen Kaplan, Los Angeles Times
Considering that he's the director of the federal agency that invests more than $30 billion in medical research each year, it may not be surprising that Dr. Francis Collins was on the Sony lot in Culver City last week for the telecast of "Stand Up to Cancer," a star-studded gala that aired live on more than a dozen TV networks and garnered more than $80 million in pledges to fund cancer research. But perhaps few viewers expected to see the head of the National Institutes of Health jamming onstage with the likes of Stevie Wonder, Kris Kristofferson, Aaron Neville and the Wilson sisters of Heart.
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SCIENCE
November 22, 2007 | Thomas H. Maugh II, Times Staff Writer
Lung transplants -- a treatment of last resort for cystic fibrosis -- are rarely beneficial to children with that condition and are often harmful, according to a study released today. Among 248 children who received a lung transplant over an 11-year period, only one clearly benefited while 167 were at a higher risk of dying after the procedure, Utah researchers reported in the New England Journal of Medicine. Dr.
SCIENCE
June 23, 2007 | From Times Staff and Wire Reports
A vaccine to prevent a dangerous infection that often strikes cystic fibrosis patients is feasible but needs more development, German researchers reported Monday in the Proceedings of the National Academy of Sciences. About 80% of CF patients become infected with the life-threatening Pseudomonas aeruginosa microbe. The experimental vaccine reduced infections by a third, according to researchers from the University of Tuebingen.
CALIFORNIA | LOCAL
March 30, 2007 | Dave McKibben, Times Staff Writer
Monique Mendoza's cystic fibrosis was so debilitating three years ago that taking a shower left her exhausted and nearly breathless. The disease had not only clogged her lungs, but also sapped her strength and spirit. "I had my funeral planned. I was OK with ... dying," said Mendoza, a 30-year-old resident of Rancho Santa Margarita. "I had already been to a lot of my friends' funerals with CF, so I knew what they were like."
HEALTH
January 23, 2006 | From Times wire reports
Mists of inhaled saltwater can reduce the pus and infection that fills the airways of cystic fibrosis sufferers, although side effects include a nasty coughing fit and a harsh taste. That's the conclusion of two studies published in the Jan. 19 issue of the New England Journal of Medicine. They found that inhaling a mist with a salt content of 7% or 9% improved lung function and, in some cases, produced less absenteeism from school or work.
CALIFORNIA | LOCAL
August 28, 2004 | Fred Alvarez, Times Staff Writer
In this summer of athletic achievement, Scott Klein's Olympic moment ended in tears on a rain-soaked track during the 4-by-100-meter relay. The race was over in less than a minute. His journey to the starting line was another story. A year ago, the 36-year-old Valencia resident could barely breathe, let alone run, after cystic fibrosis clogged his lungs and threatened his life.
SCIENCE
July 2, 2004 | Eric D. Tytell, Times Staff Writer
Reversing conventional wisdom, doctors reported Thursday that the pus and infection filling the airways of cystic fibrosis patients may stem from too little lung mucus -- not too much, as physicians always assumed. Doctors at Wake Forest University examined the phlegm in the airways of 12 patients with the disease and found very little mucus -- as little as 7% of the mucus proteins that usually coat the lungs and help shield them from bacteria.
ENTERTAINMENT
November 7, 2003 | Manohla Dargis, Times Staff Writer
French director Marina de Van's "In My Skin" opens with foxy calm. A young woman, Esther (De Van), sketches at home while her boyfriend (Laurent Lucas) nuzzles her neck and the two discuss moving in together. Then one night at a party, Esther takes a fall, tearing open one of her calves. As if under a spell, she becomes transfixed by the injury, seemingly possessed.
HEALTH
May 12, 2003 | Aaron Zitner, Times Staff Writer
Washington Scientists have long promised that the gene revolution would bring new tests to tell whether a person is particularly vulnerable to cancer, heart disease, Alzheimer's disease and other ailments. By glimpsing the weaknesses coded in their genes, the reasoning has gone, people would be better equipped to alter their diet and behavior to avoid disease.
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