June 12, 2012 |
For Terra Hillyer, who has Type 1 diabetes, enrolling in a clinical trial for a new medical device called the artificial pancreas provided a glimpse of what life might be like without the constant checks of blood sugar levels and infusions of insulin that currently mark her days. “The first thing I do when I wake up is check my blood sugar,” Hillyer says. “It is the background noise of my life.” Except for one day recently, when the mother of two checked into the Sansum Diabetes Research Institute in Santa Barbara.
June 5, 2012 |
Want to gauge your risk for developing Type 2 diabetes? Don't just step on the scale - reach for a measuring tape too, a new study suggests. The circumference of your waist can tell you a lot about your chances of getting diabetes, according to a study published Tuesday in the journal PLoS Medicine . Health providers usually rely on body mass index to determine patients' diabetes risk, but adding waist circumference to the equation would...
June 1, 2012 |
Taking the diabetes drug pioglitazone, better known by the brand name Actos, doubles the risk of developing bladder cancer, Canadian researchers have found. In absolute terms, however, the risk remains low, the researchers found -- an extra 137 cases per 100,000 person-years. According to the National Cancer Institute, there are an estimated 70,530 cases of bladder cancer in the U.S. each year and 14,680 deaths. The U.S. Food and Drug Administration warned in June 2011 that taking Actos for at least a year increased the risk of bladder cancer by at least 40%, and ordered the drug's manufacturer, Takeda Pharmaceutical North America, to note the risk on the drug's label.
CALIFORNIA | LOCAL
May 30, 2012 |
Dr. David L. Rimoin, a medical geneticist at Cedars-Sinai Medical Center who pioneered studies of dwarfism and other skeletal abnormalities, died Sunday at the Los Angeles hospital. He was 75 and had been diagnosed with advanced pancreatic cancer days earlier. Rimoin was also among the first to recognize that diabetes is caused by a variety of genetic abnormalities and he played an influential role in establishing screening programs for Tay-Sachs disease. FOR THE RECORD: An earlier version of this obituary said Dr. David L. Rimoin recruited Dr. Michael M. Kaback to Cedars-Sinai Medical Center in 1970.
May 19, 2012 |
Randy Jackson is known for providing measured critiques to aspiring singers on Fox's "American Idol," but in his private life, he's had to analyze something entirely different: After a diagnosis of Type 2 diabetes nine years ago, the music industry veteran needed to reevaluate his diet and lifestyle. Jackson went from piling his plates high with fried food and counting riding in a golf cart as exercise to eating veggies with every meal and working out every day. He talked to us about how his diagnosis changed his life and how he hopes to help others.
May 1, 2012 |
Resveratrol, the plant compound found in red wine and reputed to have anti-aging effects, including protection against cancer and diabetes, has just had a "told-you-so" moment. Resveratrol 's discoverer, the embattled Harvard professor who hopes it will point the way to new anti-aging drugs, long argued that the phytonutrient worked its magic by "turning on" the SIRT1 gene. The SIRT1 gene, one of a family of genes, the Sirtuins, is believed to control the good function and longevity of cells and, in turn, of their host.
April 11, 2012 |
Too little sleep - or disrupted sleep - seems to increase the risk of diabetes and obesity, scientists found during a recent lab experiment. Orfeu Buxton, a neuroscientist and sleep researcher at Brigham and Women's Hospital in Boston, placed 21 test subjects in isolation for nearly six weeks. For the three weeks before the experiment began, he and his colleagues instructed the volunteers to spend 10 hours in bed, to make sure they got an optimal level of sleep. Then the subjects moved into dimly lit, isolated suites in the laboratory, where the research team removed "time cues" and otherwise disrupted the volunteers' sleep, allowing them only about five hours of per 28-hour period, scattered over various times of the day and the night. Participants were not allowed visitors or Internet access. One person came in with 20 years' worth of photo-stuffed boxes and came out with well-organized photo albums, Buxton said. Another wrote a long paper.
April 8, 2012 |
Pregnant women might now have one more good reason to watch their diet and exercise: A new study links autism and developmental delays in young children to metabolic conditions, like obesity and diabetes, in their mothers. The findings, published in Monday's edition of the journal Pediatrics, found that women who had diabetes or hypertension or were obese were 1.61 times as likely as healthy women to have children with autism spectrum disorders. They also were 2.35 times as likely to have children with developmental delays.
March 31, 2012 |
Metformin is a workhorse drug for people with diabetes. It helps patients control their blood sugar and makes them more sensitive to insulin. But soon, metformin may take on a new role fighting cancer. Results of a preliminary study presented Saturday at the American Assn. for Cancer Research's annual meeting in Chicago suggest metformin slowed the growth of prostate cancer tumors. The study involved 22 men with prostate cancer. All of them were scheduled to have their prostates removed, and some of them took metformin for about seven weeks beforehand.
March 27, 2012 |
On Monday, researchers reported in two new clinical trials that several types of weight-loss surgery were more effective at controlling blood-sugar levels in obese people with diabetes than the usual care regimen of diet and drugs. In many cases, as Los Angeles Times reporter Melissa Healy wrote Monday (see related items link), surgical procedures to reduce the size and sometimes the placement of the stomach often allowed subjects to discontinue diabetes medications within weeks.