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Drug Resistance

Patients in U.S. hospitals are increasingly at risk of becoming infected with bacteria that resist treatment with antibiotics. But a new government survey has found that many hospital and clinic laboratories aren't routinely performing tests to identify some of the most dangerous drug-resistant strains. Earlier this month, the federal Centers for Disease Control and Prevention reported the fourth confirmed U.S.
The middle-aged woman was desperately ill. Brought by an anxious daughter to the emergency room at St. Joseph Medical Center in Burbank, she was nearly in a coma, her brain swelling with meningitis. Doctors swiftly put her on two antibiotics that for years have been highly effective against the disease. But she failed to improve, and lab tests showed she had a form of meningitis that resists both drugs.
September 30, 2007 | Jia-Rui Chong, Times Staff Writer
The young Army medic would not stop bleeding. He had been put on a powerful regimen of antibiotics by doctors aboard the hospital ship Comfort in the Persian Gulf. But something was wrong. He was in shock and bleeding from small pricks where nurses had placed intravenous lines. Red, swollen tissue from an active bacterial infection was expanding around his abdominal wound. His immune system was in overdrive. How odd, thought Dr. Kyle Petersen, an infectious disease specialist.
At least one in every four San Franciscans newly infected with HIV, the virus that causes AIDS, contracts a form that is resistant to one or more of the commonly used AIDS drugs, researchers said here Saturday. As a result of this resistance, it takes at least three times as long to bring these infections under control, and more complicated drug regimens are often required, said Dr. Frederick M. Hecht of UC San Francisco.
June 13, 2004 | Kathleen Doheny, Healthy Traveler
Antibiotics can be your best friend, especially when infection or traveler's diarrhea strikes in the middle of a glorious vacation. It's crucial to know which antibiotics are worth toting, how they can ease symptoms of illness and when it's wise to pop a pill. In some cases, it might even be before symptoms appear. Infectious illnesses are common in travelers but account for only 1% to 3% of deaths, says Dr. Jay Keystone, a travel medicine specialist at the University of Toronto and Toronto General Hospital in Canada who published a review of antibiotics for travelers in the February issue of the journal Current Infectious Disease Reports.
April 24, 2006 | Shari Roan, Times Staff Writer
AVOIDING the use of antibiotics in food animals appears to reduce drug resistance in humans, according to a study published online last week in the journal Clinical Infectious Diseases. The study involved the use of antibiotics called fluoroquinolones in Australian poultry. Australia restricts use of the antibiotics in animal husbandry because the practice is thought to contribute to drug resistance in people who contract bacterial infections from eating contaminated food.
December 11, 2013 | By Becca Clemons
WASHINGTON - Although malaria deaths have fallen worldwide over the last decade, health leaders warned Wednesday of a small but rising threat in parts of Southeast Asia, where anti-malaria drug resistance is confounding experts. Four countries - Cambodia, Myanmar, Thailand and Vietnam - make up an "epicenter to malarial drug resistance," said Robert Newman, the director of the World Health Organization's Global Malaria Program. Researchers have found that people in the Southeast Asia region have surprisingly high rates of resistance to artemisinin-based combination therapies, which are considered the best ways to treat the most deadly of the four types of parasites that cause malaria in humans.
December 19, 2001 | From Times Staff and Wire Reports
About half of all adults being treated for HIV infection in the United States have strains of the virus that are resistant to some of the standard drug therapies, according to a study released Tuesday. The study is the first large-scale national survey to reveal the drug resistance. Previous drug-resistance research, physicians said, focused only on smaller groups of patients. "This is very discouraging," said Dr. Samuel Bozette of the San Diego VA Medical Center, a co-leader of the study.
June 29, 2003 | Madeline Drexler, Madeline Drexler is a journalist and author of "Secret Agents: The Menace of Emerging Infections."
This month, McDonald's announced a public health breakthrough: Its meat and chicken suppliers must, by the end of 2004, stop using antibiotics to make animals grow faster. The fast-food giant's new policy doesn't go nearly far enough. But its market-driven half-measures are more visionary and practical than the timid regulations we've seen coming from the Food and Drug Administration.
September 26, 2005 | From Times wire reports
Resistance to anti-flu drugs has risen by 12% worldwide in the last decade, scientists said Thursday in a finding that could pose problems for health officials trying to avert a pandemic. Researchers at the federal Centers for Disease Control and Prevention in Atlanta found resistance to a class of drugs used to treat influenza for more than 30 years rose from 0.4% in 1994-95 to 12.3% by 2004. In some countries in Asia, drug resistance exceeded 70%.
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