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Ebola Virus

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SCIENCE
February 18, 2006 | From Times Wire Reports
The first vaccine designed to prevent infection with the lethal Ebola virus has passed initial safety tests in humans and has shown promising signs that it may indeed protect people from contracting the disease, government scientists reported. Just 21 people received the vaccine in this early-stage testing. Dr. Gary Nabel and colleagues at the National Institutes of Health's Vaccine Research Center developed a vaccine made of DNA strands that encoded three Ebola proteins.
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SCIENCE
August 23, 2010 | By Thomas H. Maugh II, Los Angeles Times
Synthetic nucleotides injected into monkeys can block the replication of Ebola and Marburg viruses, suggesting it eventually may be possible to protect humans against these deadly bioterrorism agents, researchers said Sunday. The monkeys get very sick, but most of them survive. The agents, called morpholino oligomers, are the first drugs approved by the Food and Drug Administration to go into clinical trials against the viruses — although those trials will, at least initially, be conducted in primates, not humans.
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NEWS
May 22, 1995 | Associated Press
The death toll from the Ebola virus climbed to 101 on Sunday, and health workers said the epidemic may have started as long ago as December--three months earlier than previously thought. Medical workers scouring Kikwit, a city of 600,000 where the outbreak was previously believed to have started in mid-March, found hospital records linking the virus to a household of 12 people of whom seven died in December.
ENTERTAINMENT
February 21, 2010 | By Dennis Lim
George Romero's "The Crazies" (1973) has always existed in the shadow of his zombie movies, but this epidemic thriller is perhaps the horror maestro's most provocative exploration of his great theme: the collapse of social order. A new remake, directed by Breck Eisner and also titled "The Crazies," opens Friday; the original is being issued on Blu-ray by Blue Underground on Tuesday (it is already available on standard-definition DVD). Back in the crisis-ridden early '70s, the film's queasy premise must have carried more than a ring of real-world plausibility (as it certainly does in our jittery present of viral scares and terror threats)
NEWS
November 30, 2000 | THOMAS H. MAUGH II, TIMES MEDICAL WRITER
The Ebola virus--widely feared because of its horrifying symptoms and lethal nature--may be on the verge of being tamed. Federal researchers report in today's Nature that they have devised a vaccine that fully protects monkeys against the virus--the first proof that vaccination against Ebola is possible in primates and a major step toward development of a vaccine for humans.
NEWS
April 16, 1996 | From Times Staff and Wire Reports
The deadly Ebola virus has struck two monkeys imported into Texas from the Philippines, federal health officials confirmed as they worked to contain the outbreak at a primate quarantine facility. Doctors have no reports of bites or scratches to monkey handlers at HRP Inc., in Alice, Texas, but are watching the employees carefully as a precaution, said state epidemiologist Dr. Diane Simpson. Federal experts diagnosed the illnesses as similar to the Ebola strain that decimated a Reston, Va.
NEWS
April 18, 1996 | From Times Staff and Wire Reports
Public health officials discounted any threat to humans as they euthanized 48 monkeys to contain an outbreak of the Ebola virus. One monkey had already died and another had been euthanized at the Texas Primate Center in Alice, which breeds primates for medical research. A third monkey diagnosed with the virus was being killed along with 47 others.
NEWS
May 13, 1995 | From Associated Press
Fear of contagion laced the grief of relatives who kept their death watch Friday in a cemetery where authorities handed over victims in coffins sealed to stop the spread of a dreaded virus. Two small boys in the crowd of about 50 people pulled T-shirts over their faces in a misguided attempt to protect themselves from the deadly Ebola virus that swept through Kikwit.
NEWS
May 11, 1995 | MARLENE CIMONS, TIMES STAFF WRITER
A team of federal disease detectives was dispatched to Zaire on Wednesday to investigate a deadly outbreak of what health officials strongly suspect is viral hemorrhagic fever--a devastating illness that can cause death within days by dissolving the body's organs.
NEWS
February 8, 2001 | From Times Wire Reports
A Congolese woman who arrived in Canada and fell ill does not have the Ebola virus as feared, and the danger of her sickness spreading is "minimal," health officials said after receiving test results. The woman's illness has alarmed some people since early this week, when doctors raised the possibility of Ebola and she was put into total isolation at Henderson General Hospital in Hamilton, Ontario. But health officials said at a news conference that she had tested negative for the deadly virus.
CALIFORNIA | LOCAL
February 15, 2009 | Thomas H. Maugh II
Dr. William Close, a self-proclaimed country doctor who became the personal physician of Zairian President Mobutu Sese Seko and played a key role in halting the 1976 outbreak of the lethal Ebola virus that terrified Zaire and surrounding countries, has died. He was 84. He died of a heart attack Jan. 15 at his home in Big Piney, Wyo., according to his daughter, actress Glenn Close.
SCIENCE
July 12, 2008 | From Times Staff and Wire Reports
Ebola, the mysterious virus responsible for periodic deadly outbreaks of hemorrhagic fever in Africa, may have an Achilles' heel, scientists at Scripps Research Institute in La Jolla reported Thursday. Writing in the journal Nature, researchers revealed the shape of a protein that the virus uses to enter healthy cells, providing a possible target for drugs. Scientists also discovered some parts of the virus are similar in structure to parts of the HIV and Epstein-Barr virus, suggesting Ebola may help scientists understand why some diseases manage to avoid the body's defenses.
SCIENCE
December 8, 2007 | From Times Staff and Wire Reports
Uganda has 101 suspected cases of Ebola fever and hundreds more people being closely monitored, officials said Friday, as fear grew there and in neighboring countries that the deadly virus might spread. Twenty-two people have died of the fever, said Dr. Emmanuel Otaala, minister of state for primary healthcare, and 11 health workers have fallen sick.
SCIENCE
February 18, 2006 | From Times Wire Reports
The first vaccine designed to prevent infection with the lethal Ebola virus has passed initial safety tests in humans and has shown promising signs that it may indeed protect people from contracting the disease, government scientists reported. Just 21 people received the vaccine in this early-stage testing. Dr. Gary Nabel and colleagues at the National Institutes of Health's Vaccine Research Center developed a vaccine made of DNA strands that encoded three Ebola proteins.
SCIENCE
December 1, 2005 | Alex Raksin, Times Staff Writer
Researchers working in Gabon and Congo have identified three species of fruit bat as the long-sought reservoirs of one of the deadliest known human pathogens, the Ebola virus. The team tested more than 1,000 bats and other animals before tracing the virus to fruit bats, which are commonly eaten by people in Central Africa, according to a report in today's issue of the journal Nature. Researchers found minute genetic traces of the virus in 22.6% of the bats tested.
OPINION
May 10, 2004 | Laurie Garrett
As the horrors of Sudan's ethnic conflict mount, opportunities for pathogenic microbes -- germs that could threaten people all over the world -- rise in tandem. War and disease are often a matched set in Africa, with terrifying results: If the fighting doesn't kill you, disease very well could. And without outside help to stop the cycle, the devastating results will only spread.
WORLD
June 26, 2002 | From Times Wire Reports
Experts investigating a possible outbreak of the deadly Ebola virus in the Republic of Congo have found four suspected cases in neighboring Gabon, the World Health Organization said. Two people died and two were sick with Ebola-like symptoms in Ekata in the remote north of the West African nation, WHO spokeswoman Fadela Chaib said. Six similar cases, including five deaths, already had been reported in the Republic of Congo.
NEWS
December 6, 1989 | From Times Staff and Wire Reports
Hazleton Research Products, a Reston, Va., research laboratory where monkeys were found to be infected with a rare and deadly virus, said that precautionary testing found all of its employees to be free of the disease. The company sent workers' blood samples to the national Centers for Disease Control in Atlanta for analysis after one man who handled monkeys infected with the Ebola virus became ill and was placed in isolation at Fairfax Hospital.
OPINION
January 27, 2004
In light of the resignation of chief Iraq weapons inspector David Kay (Jan. 24) and his assertion that no weapons of mass destruction existed in Iraq, the search is on for the cause of the intelligence failure that led to President Bush's pre-war assertion about Iraq's massive WMD effort. Kay has cast a significant shadow of doubt on the major justification for the war. Perhaps, in time, the alleged intelligence failure may also prove to be a phantom, for one has to wonder if it was the intelligence itself or the interpretation thereof that led to the president's conclusion that war was necessary.
SCIENCE
December 13, 2003 | From Times Staff and Wire Reports
The first treatment to show any promise against the deadly Ebola virus has cured one-third of the monkeys it was tested on -- raising hopes that a lifesaving therapy for people may be on the horizon. In the study, reported this week in the research journal Lancet, scientists at the U.S. Army Medical Research Institute of Infectious Diseases used a protein that blocks blood coagulation, considered to be a major problem in the disease.
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