May 18, 2009 |
It turned a whole town into a research lab. It was the first to show the world that high cholesterol and obesity put people at risk for heart disease -- the first, in fact, to coin the very term "risk factor." And it still hasn't run out of juice. The longest-running heart health study in the world, the 60-year-old Framingham Heart Study, continues to mine its vast data set for causes or signs of heart trouble.
June 18, 1989
Joseph Stokes III, 64, one of the principal investigators of the world's longest-running heart study and the first dean of the medical school at UC San Diego. A cardiologist and epidemiologist, Stokes was an investigator for the renowned Framingham Heart Study which began in 1948 with 5,209 residents of the central Massachusetts city of Framingham. The project monitors patterns, causes and inhibitors of cardiovascular disease and remains the world's longest running project of its kind.
August 1, 2011 |
Pop quiz: Which of the following causes the brain to shrink? 1) diabetes 2) smoking 3) high blood pressure 4) being overweight in middle age? Answer: All four. That's the latest word from the famous Framingham Heart Study , an investigation of residents of a Massachusetts town that's been going on since 1948. This particular report, published in the journal Neurology, tracked 1,352 people with an average age of 54 for years. All were offspring of the original set of Framingham residents who agreed to join the study.
November 1, 2012 |
A twenty- or thirtysomething adult with blood pressure that's even a little high is risking damage to the structural integrity of his brain that may be evident by the age of 40, says a new study. The early appearance of hypertension's toll on the brain suggests that physicians should act sooner and more aggressively to control the upward creep of blood pressure in their younger patients, say the authors of the latest research, published online in the Lancet on Thursday. Neurologists at UC Davis led a study that looked at 579 third-generation participants of the famous Framingham Heart Study.
November 13, 2010 |
Having a relative who developed atrial fibrillation -- an uncontrolled fluttering of the heart that makes it difficult to pump blood -- before the age of 65 triples your risk of developing the condition, researchers said Saturday. If the relative develops the condition after the age of 65, your risk is increased by 40%, independent of other risk factors, they reported at a Chicago meeting of the American Heart Assn. and online in the Journal of the American Medical Assn. Researchers knew that the risk of developing the disorder had a hereditary component, but they did not previously know how large the risk was. An estimated 2.2 million Americans suffer from atrial fibrillation, which is caused by erratic electrical signals triggering contractions of the heart.
July 8, 2010 |
Is sadness a sickness? It appears to spread like one, a new study has found. Researchers at Harvard University and MIT wanted to see if a mathematical model developed to track and predict the spread of infectious diseases such as SARS and foot-and-mouth disease could also apply to the spread of happiness -- and found that it worked. They used data collected from 1,880 subjects in the Framingham Heart Study, a long-term research effort that has followed subjects since 1948 (and added some new ones along the way)