November 29, 2000 |
Another drug launched with "fast-track" government approval was withdrawn on Tuesday, marking the 10th time in three years that a prescription medicine has been banished in the United States for safety reasons. The drug, Lotronex, was approved nine months ago for treating irritable bowel syndrome in women. The withdrawal was announced by Glaxo Wellcome Inc. after the Food and Drug Administration received voluntary reports linking the company's drug to five deaths and additional bowel surgeries.
December 10, 1998 |
Sufferers of liver-destroying hepatitis B gained their first oral treatment: a drug that in higher doses is used to fight the AIDS virus. The Food and Drug Administration approved a lower dose of Glaxo Wellcome Inc.'s 3TC, or lamivudine, as a way to protect against the liver damage caused by chronic hepatitis B.
August 25, 2000 |
The government is sending to women's homes a major warning about a popular new treatment for irritable bowel syndrome: The drug Lotronex sometimes causes severe intestinal side effects--some requiring surgery--so stop taking it at the earliest sign of a problem. Hoping to help women safeguard themselves, the Food and Drug Administration announced it has ordered Glaxo Wellcome Inc. to attach to every Lotronex bottle a pamphlet explaining the risk.
April 7, 1997 |
Ulcer patients that have long relied on Zantac to ease their pains will soon have a generic alternate on the market at half the price they now pay, Novopharm USA Inc. executives said. A federal appeals court ruled Friday that the generic drug would not violate two Glaxo Wellcome Inc. patents on Zantac, which as the world's best-selling prescription medicine had sales of $1.63 billion in the United States last year.
April 22, 1999 |
Merck & Co., Glaxo-Wellcome Inc., Bristol-Myers Squibb Co. and 14 other drug companies will give away $148 million worth of products in California during the next three years to settle allegations they conspired to fix the price of prescription brand-name drugs. The drug makers were accused in the class-action suit of overcharging California consumers for drugs purchased through retail pharmacies since 1990.
July 7, 1999 |
A new drug inhaled once a day during flu outbreaks may help prevent people from becoming infected with either A or B strains, an improvement over older drugs, researchers said. According to a study in the July 7 issue of the Journal of the American Medical Assn., half of about 1,100 healthy adults inhaled 10 milligrams of zanamivir, also called Relenza, once a day for four weeks during the 1997-98 flu season. The other half were given a fake dose. Dr.