History

The Food and Drug Administration on Thursday cautioned consumers against using quinine for leg cramps, warning that the drug could cause severe side effects, including death. Quinine, sold in this country under the brand name Qualaquin, is approved for treatment of uncomplicated malaria, but has a long history of use as a remedy for leg cramps, especially at night. In many countries, it is sold over the counter. Studies have shown that it can reduce the incidence of cramps by one-third to one-half but that as many as one in every 25 users can suffer serious side effects.

Memorial Day is a day off for many of us, so as you're lighting the fire and throwing another burger on the grill, consider this quiz, which talks about the meaning of the day. If you get all 10, well, pop open a beverage and have another dog. 1. Memorial Day was originally called something else. What was it? a.  Day of the Dead b. Remembrance Day c. Decoration Day d. Armistice Day 2. During what war did the day originate? a. Revolutionary War b. Civil War c. World War I d. Korean War 3. Several places claim they are the real founders of the day. Which place in the South might have been the earliest adopter?

Researchers have some reassuring news for the legions of coffee drinkers who can't get through the day without a latte, cappuccino, iced mocha, double-shot of espresso or a plain old cuppa joe: That coffee habit may help you live longer. A new study that tracked the health and coffee consumption of more than 400,000 older adults for nearly 14 years found that java drinkers were less likely to die during the study than their counterparts who eschewed the brew. In fact, men and women who averaged four or five cups of coffee per day had the lowest risk of death, according to a report in Thursday's edition of the New England Journal of Medicine.

  Your browser does not support iframes. It was 10 years ago today, Shawn Green taught the band to play -- no, wait, may I reintroduce to you possibly the single greatest offensive day by a player in major league history? Green was a struggling disappointment 10 years ago, that sweet swing suddenly vanished without explanation. He had been booed in his last home game. But then came May 23, 2002 in Milwaukee. And by the end of the day, Green was rewriting the record books.

Manny Hamelburg, 68, a retired businessman, had fought prostate cancer for years. First, he tried radiation, then a drug with side effects that nearly killed him, and finally Lupron, a drug that blocks production of testosterone, the hormone that can fuel prostate cancer. The cancer disappeared. But life was miserable. Without normal levels of testosterone, Hamelburg says, he had no energy, and "zero libido for seven years. I was like a eunuch. I was chemically castrated. Sex was just hugs."

washington -- Mitt Romney twice emphasized his unique business background when he and eight other Republican presidential candidates faced off in a debate last week in Iowa. "I've spent the last, as I've told you, 25 years in the private sector," former Massachusetts Gov. Romney declared at one point. "I understand why jobs come and why jobs go. I've done business in 20 countries."

The wait for tables is getting longer at Buck's, a popular breakfast spot for the tech elite and a weather vane for the Silicon Valley economy. Here, like everywhere else, Facebook is the talk of the town. "Charles Schwab was in the restaurant the other day, and I asked him to hook me up with some Facebook shares," said Jamis MacNiven, owner of Buck's, in the wealthy suburban enclave of Woodside. "He told me even he can't get Facebook shares. " The new tech boom officially gets underway Friday when Facebook Chief Executive Mark Zuckerberg rings Nasdaq's opening bell remotely from the company's Menlo Park, Calif., headquarters, launching the largest initial public offering of stock in Silicon Valley history.

Pop star Andy Gibb died of natural causes--an inflammation of the heart probably caused by a virus--and not from a drug overdose or alcohol abuse, a hospital announced Friday. Gibb died at Oxford's John Ratcliffe Hospital on Thursday, five days after his 30th birthday. He entered the hospital Monday complaining of stomach pains.

There wasn't much to like about Facebook's first day as a public company. The social media giant's stock rose by mere pennies in its initial public offering. The shares closed at $38.23, barely above the $38 IPO price. The performance fell far short of the grandiose expectations of Wall Street and Silicon Valley, and raised questions about whether the company's stock will be the sure bet many had counted on. "There was all this pressure and hype and attention with all eyes on Facebook — and the starlet tripped on the red carpet," said Max Wolff, an analyst at GreenCrest Capital Management in New York.

Bob Kahl slips in through a side door of the vast, abandoned hangar and looks at what's left of the assembly plant where he worked for nearly 40 years. He remembers the hum of power tools, the biting aroma of cutting oil, swarms of workers plugging away on a labyrinth of yellow scaffolding. All that's left is a few piles of broken concrete and a sea of colorless dust that coats a Palmdale factory floor the size of two football fields. "Welcome to the birthplace of America's space shuttle fleet," said Kahl, 60, smiling.

A federal appeals court in Washington has upheld a key part of the Voting Rights Act, one that requires states and localities with a history of discrimination against minorities to "pre-clear" changes in their election procedures with the Department of Justice or a federal court. The reasoning behind the 2-1 ruling is persuasive; Chief JusticeJohn G. Roberts Jr.and other members of the Supreme Court should exercise judicial restraint by refusing to reconsider it. In an earlier, 2009 decision, the chief justice recognized that Congress has the power to enforce the 15th Amendment's guarantee of a right to vote.

You can draw a straight line, in terms of architectural history, from William Randolph Hearst'ssprawling estate in San Simeon to the corner of Broadway and 11th Street in downtown Los Angeles. It was at that downtown site in 1913 that Hearst commissioned architect Julia Morgan to design a headquarters for his Los Angeles Examiner newspaper, which he'd founded in 1903. Morgan produced one of the most remarkable designs of her prolific career, a 103,500-square-foot Mission Revival building draped with Italian and Moorish touches, including domes covered in yellow and blue tile.

BALTIMORE -- The amazing story moved up to incredible. I'll Have Another ran true to his name. On a Saturday that brought blue skies, perfect temperatures and a record crowd of 121,309 here at venerable Pimlico racetrack, the horse who has never been favored in a race and has been mostly under-appreciated by the public, even the racing public, won the 137th Preakness. Now, it is I'll Have Another who will take a shot at history. The last horse to win the Triple Crown was Affirmed in 1978.

BALTIMORE -- Triple Crown horse racing season is a respite. It allows a deep breath for a sport that is desperately seeking reason. The Preakness is similar to pro golf's Saturday. They call it moving day, because it is the last chance to get in position for the big prize. The difference is that, when 11 horses load into the gate here Saturday afternoon, only one can land the big prize, the Triple Crown. That one, Kentucky Derby winnerI'll Have Another, is not only a horse to be admired, but a story with lots of weird chapters.

Deep inside my writerly brain, down where my earliest memories reside, there is a voice. It speaks to me in Spanish. I write in the language of Shakespeare and Steinbeck. That's the language I was educated in, here in L.A. The language of the British Empire, of American Manifest Destiny, of California and the West. But Spanish gave me my first words: mamá, agua . And it was the language on the covers of the first works of grown-up literature I held in my hands, the Guatemalan novels my immigrant father brought into our Hollywood home.

Re "A woman's touch," Opinion, May 11 Why is it such an amazing idea that "mom" might have some answers on running a business? Thousands of years of patriarchal dominion, with men's values of "assertiveness, competitiveness and even aggression," have given us endless wars, price-gouging, indecent pay inequalities, discrimination, concentration camps, slavery, child labor, class warfare and holocausts. If women had had a public voice these past few thousand years, what kind of world would we have?

There's so much to praise in the blissful Broadway revival of "Follies," which opened Wednesday at the Ahmanson Theatre on the heels of its numerous Tony nominations, but let's pay homage first to the sheer sophistication of the show itself. After experiencing "Follies" again - an adult entertainment if ever there was one - I flat-out refuse to accept any more jukebox substitutes. One doesn't often talk about architecture when writing about musicals, but the most impressive thing about "Follies," beyond Stephen Sondheim's bejeweled score, is the ingenious way it is constructed.

Lipitor is the most prescribed name-brand drug in America - nearly 3.5 million people take it every day to control their cholesterol. Since the statin entered the market in 1997, it's earned New York-based pharmaceutical giant Pfizer Inc. $81 billion, making it the best-selling prescription drug of all time, according to IMS Health, a Danbury, Conn.-based healthcare information company. So when Lipitor's patent protection came to an end Nov. 30 and a generic alternative became available, an awful lot of patients had a decision to make: Should they stick with the drug they knew or switch to something less expensive?

SAN ANSELMO, Calif. — Days after President Obama announced his support for same-sex marriage, the Presbyterian Church's Northern California governing body refused to rebuke a retired minister for marrying gays and lesbians when it was legal in California. The Presbytery of the Redwoods, which governs churches from the Golden Gate Bridge to the Oregon border, voted 74 to 18 Tuesday to reject the church's official denunciation and instead support the Rev. Jane Adams Spahr, who had been found guilty by an ecclesiastical court of violating the Presbyterian Constitution and her ordination vows for marrying 16 same-sex couples.

It would be impossible to count the number of automotive makes and models that have come and gone since the car was first invented - or the number of books that have been written about them. The inescapable ubiquity of the automobile has made them, for better or worse, a sort of cultural fodder that Pulitzer Prize-winning journalist Paul Ingrassia inventively exploits in "Engines of Change. " The question at the center of his nonfiction treatise: Do cars shape the culture, or does culture shape the cars?