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Hormones

HEALTH
March 7, 2012 | By Shari Roan, Los Angeles Times
Many women who used estrogen alone as hormone replacement therapy after menopause had a lower risk of developing breast cancer up to five years after they stopped taking it, a study has found. The research, published Tuesday, adds another twist to the evolving story on whether hormone replacement therapy helps some women beyond treating menopausal symptoms such as hot flashes and poor sleep quality. The report is a follow-up analysis of the landmark Women's Health Initiative, a clinical trial of tens of thousands of women begun in 1993 that sought to clarify the risks and benefits of two hormone replacement therapy regimens in postmenopausal women: estrogen plus progestin, which most women must take, and estrogen alone, taken by women who have had hysterectomies.
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NEWS
March 6, 2012 | By Shari Roan, Los Angeles Times / For the Booster Shots blog
Perhaps if there were other really effective medications to treat menopausal symptoms people wouldn't care so much about the safety of hormone replacement therapy. But there aren't medications that work as well as estrogen alone (for women who have hysterectomies) or estrogen plus progestin (for those with a uterus) to stop hot flashes, night sweats, sleep problems, foggy thinking, vaginal dryness, mood swings and other problems that crop up for some women during the menopausal transition.
ENTERTAINMENT
February 16, 2012 | By Mark Olsen, Special to the Los Angeles Times
It might be wintry cold this time of year in Brussels, but on a recent February afternoon in Los Angeles, it was sunny, warm and near-perfect as Belgian writer-director Michaƫl R. Roskam and actor Matthias Schoenaerts sat at a table poolside at a Sunset Strip hotel, each laying into a plate of steak frites as women in swimsuits and the men who chase after them circulated nearby. It was more or less a scene straight from "Entourage," the fantasy version of itself Hollywood likes to export around the world.
CALIFORNIA | LOCAL
January 18, 2012 | By Dennis McLellan, Los Angeles Times
Wylie W. Vale Jr., a professor at the Salk Institute for Biological Studies in La Jolla and an internationally renowned expert on brain hormones who led a team of Salk researchers that discovered the brain hormone that triggers the body's reaction to stress, has died. He was 70. Vale died unexpectedly in his sleep Jan. 3 while on vacation in Hana on the Hawaiian island of Maui, said his wife, Betty. The cause of death has not been determined. The Texas-born Vale, who joined the Salk Institute in 1970, became one of the world's leading authorities on peptide hormones and growth factors that provide communication between the brain and endocrine system (the organs that produce the body's hormones)
NEWS
January 13, 2012 | By Melissa Healy, Los Angeles Times/For the Booster Shots blog
Remember this name: irisin. A newly described polypeptide hormone named after the Greek messenger goddess Iris, irisin may one day play a role in defeating the twin epidemics of obesity and Type 2 diabetes. It made its debut on Thursday in the journal Nature . To understand how irisin might help the lumbering masses lose mass, it helps to remember that mammalian fat comes in (at least) two colors. Brown is the new black: It's what you want more of. Unlike the white fat that lards the thighs and jiggles dangerously across the belly, brown fat's the stuff that boosts a mammal's energy expenditure.
SPORTS
December 1, 2011 | By Lance Pugmire
Reporting from New York - The head of the World Anti-Doping Agency chided the NFL Players Assn. on Thursday for not giving a green light to testing players for human growth hormone. "It seems [the union's objection] is not based on science," WADA chief David Howman said. "You're better [off] to expose yourself to a test than decline it, because the impression you leave is that you have something to hide. " The new NFL labor contract allowed HGH testing as early as this season but only if the players' union approved the tests.
SPORTS
November 22, 2011 | By Phil Rogers
Live long enough, you'll see everything. One of America's major sports just announced a new collective bargaining agreement. It is the same one that is expanding its drug testing program to become the first to include blood testing for human growth hormone. And that sport is baseball. Where have you gone, Pete Rozelle? You too, the young David Stern? Baseball lost the 1994 World Series to civil strife between small-market clubs and large-market clubs and a 25-year war with the players union.
NEWS
November 4, 2011 | By Shari Roan, Los Angeles Times / For the Booster Shots blog
A significant rise in hip fractures among women is one result of the decade-long slide in the popularity of hormone replacement therapy, researchers report in a new study. The landmark Women's Health Initiative study showed unequivocally that hormone therapy helps strengthen women's bones and prevents fractures of hip, wrist and spine by 27% to 35%. However, hormone use fell out of favor after studies in 2002 showed it raised the risk of breast cancer and did not lower heart-disease risk and, in fact, may elevate the risk in some women.
HEALTH
October 27, 2011 | Melissa Healy
As if Americans needed any reminder that weight loss is hard and maintaining weight loss even harder, a study has found that for at least a year, subjects who shed weight on a low-calorie diet were hungrier than when they started and had higher levels of hormones that tell the body to eat more, conserve energy and store away fuel as fat. The report, published Wednesday in the New England Journal of Medicine, helps explain why roughly 4 in 5...
NEWS
October 4, 2011 | By Shari Roan, Los Angeles Times / For the Booster Shots blog
Brown fat has been a hot topic in obesity research in recent years. So has a hormone produced in the brain called orexin. Now scientists have linked these two concepts in a theory that may lead to new weight-loss therapies. Brown fat is a healthy substance that contains blood vessels and helps burn fat. People who are obese are thought to have less-active brown fat. Orexin is a hormone that is known to play a role in controlling appetite. In a paper published Tuesday, scientists have shown that orexin also activates brown fat to burn calories.
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