CALIFORNIA | LOCAL
January 10, 1998 |
Marianne Whitmyer first noticed the changes in her fingers and her tongue. They looked the same but no longer worked the same, her fine motor control dissolving after two decades as a professional flutist. The problem, doctors discovered early last year, is that Whitmyer's brain is dying. Whitmyer, principal flute and soloist with the Irvine Symphony, suffers from Huntington's chorea, or Huntington's disease, a progressive hereditary illness that leads to death.
October 9, 2000 |
In the long, difficult struggle to understand--and do something about--the brain ailment called Huntington's disease, scientists have decided the best approach may be to go fishing. The target is a strange jellyfish that has a natural ability to glow in the dark when pestered, showing its irritation in eerie green light. The glow, they hope, will lead toward a cure for Huntington's disease, a fatal brain disorder first noted among people living on the eastern tip of Long Island, N.Y.
October 28, 2001 |
A surprising and provocative study of brain tissue from people with Huntington's disease offers clues on how a defective gene causes the disorder and how it might be treated. About 30,000 Americans have HD, which generally appears between ages 30 and 45. It slowly hampers a person's ability to walk, think, talk and reason. Eventually, an affected person becomes totally dependent on others, and death usually follows from complications of the condition.
August 8, 1997 |
Four years after the discovery of the defective gene that causes Huntington's disease, researchers have produced the first clues about how the gene causes the devastating disorder. That new insight, experts say, could quickly lead to the first successful treatments not only for Huntington's, but also for half a dozen other diseases that have an identical genetic defect.
CALIFORNIA | LOCAL
September 11, 1993
A UC Irvine biological chemistry professor is a member of an international research team that on Wednesday won the National Medical Research Award. Prof. John Wasmuth will share the prestigious award with six other scientists. The seven make up the Huntington's Disease Collaborative Research Group. The group was honored for discovering the gene responsible for Huntington's disease. The award was presented by the National Health Council.
May 21, 1989 |
Ever since it became clear that the United States would launch a massive project to identify every one of the estimated 100,000 genes in the human body, scientists from laboratories throughout the country and around the world have vied to get in on the ground floor. Even though a formal plan for the $3-billion project will not be assembled until later this summer, two recent meetings--one here at the Cold Spring Harbor Laboratory and a conference in Washington--quickly demonstrated that scientists have already begun several key experiments.