July 27, 2004 |
Mylan Laboratories Inc., one of the world's biggest makers of generic drugs, has agreed to acquire King Pharmaceuticals Inc. for about $3.37 billion in stock to expand its branded drug business, the companies said Monday. The transaction was not welcomed by Mylan's shareholders, who sent the company's shares down more than 16% amid concern that King is not worth the price. King's most important product is Altace, a drug for hypertension that generates annual sales of about $450 million.
CALIFORNIA | LOCAL
July 17, 2004 |
Dr. Arthur J. Moss, 90, professor emeritus at the David Geffen School of Medicine at UCLA and an internationally recognized authority in the field in pediatric hypertension, died Wednesday of kidney failure at his home in Los Angeles, according to a UCLA representative. Moss made impressive contributions in pediatric cardiology, among them his findings on cardiovascular changes in newborns.
June 7, 2004 |
Once considered a disease of middle age and later years, high blood pressure actually has its roots in early childhood. Those roots are now present in an increasing number of children and teens. "What we're finding is that with the current epidemic of overweight and couch-potato children, a higher percentage than ever before are in the hypertensive range," said Dr. Julie R. Ingelfinger, a pediatrics professor at Harvard Medical School.
December 15, 2003 |
High blood pressure has long been linked to obesity, smoking and family history, but doctors now have compelling evidence that inflammation also may be a contributing factor. The findings, if confirmed by further research, might help doctors identify people at risk of hypertension before their blood pressure readings start to rise. Hypertension afflicts about 50 million Americans, many of whom aren't aware of its health toll.
June 2, 2003
The article "A Clue to Why Less Salt Is Better" (May 26) explains why eating fruits, vegetables and low-fat dairy foods is effective in lowering blood pressure. This type of diet is considered part of the DASH, or Dietary Approaches to Stop Hypertension, which was introduced nearly six years ago. What I found interesting about this article was the fact that only recently researchers have discovered why this kind of diet actually works, yet six years ago doctors were prescribing it as a way to lower blood pressure as well as treat hypertension.
April 23, 2003 |
In a highly unusual action, the Journal of the American Medical Assn. is publishing incomplete results today from an aborted drug trial, along with a scathing editorial blasting the drug's manufacturer for halting the trial. The massive trial enrolled 16,602 patients in 15 countries in a five-year effort to determine whether the anti-hypertension drug verapamil is better than less expensive diuretics and other drugs. But Pharmacia Corp.
April 23, 2003 |
A study that tested the impact of a combination of lifestyle changes on high blood pressure found that it can be lowered without drugs, researchers said Tuesday. The beneficial changes in the study required 180 minutes of moderately intense exercise per week, a reduced-fat diet featuring more fruits and vegetables, weight loss of at least 15 pounds, reduced sodium intake and limiting alcoholic beverages to one per day for women, two for men.
April 21, 2003 |
In December, a study of more than 42,000 white and black Americans found that old-fashioned, cheap diuretics -- "water pills" -- work at least as well and sometimes better than more expensive drugs to treat high blood pressure and certain heart problems. In February, a study of more than 6,000 mostly white Australians came to a different conclusion -- that drugs called ACE inhibitors were better than diuretics, although only for men (for unclear reasons).
CALIFORNIA | LOCAL
April 17, 2003 |
Dr. Arthur C. Guyton, a cardiovascular physiologist who was an expert on hypertension and author of a popular medical textbook and who inspired all 10 of his children to become doctors, has died. He was 83. Guyton died April 3 in an automobile crash near his home in Jackson, Miss. His wife of 59 years, Ruth, died Thursday of injuries she suffered in the crash. Born in Oxford, Miss., the son of a doctor father and missionary teacher mother, Guyton set out to become a heart surgeon.