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Irritable Bowel Syndrome

SCIENCE
August 31, 2012 | By Thomas H. Maugh II
The Food and Drug Administration on Thursday approved a new drug, Linzess, to treat irritable bowel syndrome with constipation. The drug, known generically as linaclotide, speeds up bowel movements and reduces pain in many patients with the disorder. It is the second product on the market aimed at the population, following Amitiza (lubiprostone), which was approved in January 2006 but may have more side effects than Linzess. An estimated 15.3 million Americans suffer from irritable bowel syndrome with constipation, according to the National Institutes of Health, and about 63 million suffer from constipation.
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HEALTH
December 23, 2002 | Dianne Partie Lange
Hypnosis has been so effective in treating irritable bowel syndrome that British researchers recently tested its usefulness for chronic indigestion. More than 100 people at the Wythenshawe Hospital in Manchester, England, were assigned to receive 12 30-minute sessions of either hypnotherapy, supportive therapy and a placebo medication, or medication (rantidine twice a day) over 16 weeks.
OPINION
November 12, 2000
Re "FDA Minimized Issue of Lotronex's Safety," Nov. 2: It is untrue that Glaxo Wellcome and the FDA have not taken seriously reports of adverse events among women who have taken Lotronex. Both Glaxo Wellcome and the FDA apply the world's highest standards in our efforts to make innovative medicines available. We both have independently scrutinized the benefits and risks and have concluded that, in appropriate patients, Lotronex has a demonstrated benefit in the treatment of diarrhea-predominant irritable bowel syndrome, which can be severely incapacitating.
BUSINESS
August 20, 2001 | Bloomberg News
Novartis, Europe's third-biggest drug maker, needs to win U.S. approval for the experimental medicine Zometa to start turning around a 18% drop in shares this year, analysts and investors said. The Food and Drug Administration may rule today on the drug, designed to treat a life-threatening condition in which too much calcium enters the bloodstream. The U.S. agency has been reviewing additional data after last year deeming Zometa "approvable."
OPINION
June 1, 2007
Re "You know what makes me sick?" Opinion, May 27 As a practicing gastroenterologist and a board member of the Celiac Disease Foundation, I find it unfortunate that Heather Abel accuses physicians of pushing pills after being bought off by drug companies. The failure to diagnose celiac disease is because of symptoms (if any) that are typically subtle and nonspecific, not because of a conspiracy between physicians and drug companies. Abel says her irritable bowel syndrome was treated with Celebrex, which caused ulcers.
HEALTH
December 8, 2003 | Elena Conis
Peppermint is approved in Europe for treating colds, coughs, dyspepsia and liver conditions. In this country, the hardy perennial is often found in herbal remedies for stomach ailments and is sold as a dietary supplement. The herb's main ingredient is menthol, but it also contains flavonoids such as limonene. * Uses: Some herbalists recommend the herb or its oil for colds, coughs and headaches. It's also sometimes used to ease upset stomachs, irritable bowel syndrome and indigestion.
HEALTH
October 22, 2001 | Jane E. Allen
The next time your gut goes to pieces after a meal, it may turn out that fruit was the source of all that digestive distress. Doctors have long recognized that lactose intolerance--an ability to digest milk sugar--is responsible for some of the irritable bowel syndrome that plagues about 10% of all Americans.
NEWS
April 24, 2002 | From Associated Press
Government advisors heeded patients' pleas Tuesday that a drug for irritable bowel syndrome should be cleared for sale again--but with stringent restrictions to try to mitigate side effects that have hospitalized more than 160 people and killed seven.
HEALTH
April 16, 2007 | Chris Woolston, Special to The Times
I receive a lot of ads in the mail for Flora Source, a probiotic. Will it do everything the ads claim? PEARL Wildomar The product: If our bodies ran by majority rule, we'd all be slaves to bacteria. By some estimates, the average digestive tract contains 750 trillion bacteria -- enough to outnumber the human cells in your entire body by about 7 to 1.
NEWS
January 22, 1985 | SALLY SQUIRES, Newhouse News Service
Almost everyone suffers from it at some time--that bloated feeling, or the kind of uncomfortable sensation that comes from overeating or indulging in too much greasy food. Sometimes it's accompanied by nausea and often it's over in a matter of hours. What everyone knows as indigestion has been treated light-heartedly in numerous television commercials. But chronic indigestion can be a far more serious signal of other digestive diseases, ranging from a peptic ulcer to irritable bowel syndrome.
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