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HEALTH
December 4, 2010 | By Amina Khan, Los Angeles Times
Have scientists finally discovered the genetic fountain of youth? Hardly. But by creating a genetic switch that allows them to artificially age — and rejuvenate — lab mice, scientists have shown that it is possible to reverse some effects of aging in mammals. "It indicates there's a point of return if you remove the underlying cause of the aging," said Dr. Ronald DePinho, the molecular biologist at the Dana-Farber Cancer Institute at Harvard Medical School who led the study, published online this week in the journal Nature.
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SCIENCE
May 18, 2012 | By Melissa Healy, Los Angeles Times
In an age of long commutes, late sports practices, endless workdays and 24/7 television programming, the image of Mom hanging up her dish towel at 7 p.m. and declaring "the kitchen is closed" seems a quaint relic of an earlier era. It also harks back to a thinner America. And that may be no coincidence. A new study, conducted on mice, hints at an unexpected contributor to the nation's epidemic of obesity - and, if later human studies bear it out, a possible way to have our cake and eat it too, with less risk of weight gain and the diseases that come with it. Just eat your cake - or better yet, an apple - earlier.
HEALTH
October 8, 2007 | Karen Ravn, Special to The Times
This antioxidant can protect against cancer, heart disease and diabetes. It can lower cholesterol, reduce inflammation and ease pain. Best of all, perhaps, it can help users live 30% longer than they would without it. Resveratrol -- a substance found most notably in red wine -- is sometimes called a "miracle molecule." In labs around the world, scientists are devoting their lives to studying it, and they're writing so many papers about it that mere mortals are hard-pressed to keep up with them all. In short, the evidence is nearly overwhelming that resveratrol can work wonders for your health.
NEWS
May 23, 2011 | By Melissa Healy, Los Angeles Times/ For the Booster Shots Blog
Steady exposure to the electromagnetic radiation given off by cellphones during use may disrupt fetal development, disturb memory and weaken the barrier that protects the brain from environmental toxins, says a welter of new research being presented this week in Istanbul, Turkey. The authors of the studies, published in the past two years, highly preliminary and conducted on rabbits, mice and rats, suggested that the non-ionizing radiation emitted by cellphones and the base stations that broadcast cellphone signals may fundamentally damage cells by means other than the heat that they generate.
SCIENCE
May 20, 2013 | By Amina Khan
A crew of Mongolian gerbils may have gone where no Mongolian gerbil has gone before, but they did not come back alive. A Russian spacecraft filled with mice, lizards and other animals has returned to Earth -- but with the majority of its furred passengers apparently dead. The Bion-M experiment, launched from Baikonur, Kazakhstan, on April 19, carried 45 mice, 15 geckos, 18 Mongolian gerbils, 20 snails and a number of different plants, seeds and microorganisms, according to a Russian state news site .  About half of the mice died, but the lizards reportedly survived.
SCIENCE
July 2, 2013 | By Geoffrey Mohan
[This post has been corrected. See note at bottom.] A federally approved drug already being inhaled by asthma patients may make mice with Down syndrome smarter, according to a new study. Researchers chose to test the widely manufactured bronchodilator, Formoterol, because it also acts on a brain chemical crucial to memory-based learning. Earlier research had shown a similar compound successfully stimulated production of that brain chemical, called a neurotransmitter, which then improved neuron formation and cognition in mice that had been genetically altered to show symptoms of Down syndrome, according to Dr. Ahmad Salehi, a Stanford University neurobiologist who led the study, published Tuesday in the journal Biological Psychiatry.
NEWS
April 8, 2011 | By Shari Roan, Los Angeles Times
Drinking at a young age is simply bad for the brain, according to a growing number of studies. The latest study looks at the relationship between alcohol and the brain in mice. And the results are not pretty. Researchers gave mice alcohol daily for 10 days and later examined their brains with MRI. The mice who were drinkers in youth had smaller forebrain volume and size as adults. The study also found reduced activity in some genes that govern brain chemicals called neurotransmitters 24 hours after an alcohol binge in adolescent mice.
NEWS
December 21, 2010 | By Tami Dennis, Tribune Health
Hexavalent chromium. The term sounds high-tech and slightly ominous to those unfamiliar with it -- and apparently few people are familiar with it. Hexavelent chromium is currently piquing online readers' curiosity. The highly publicized specter of potentially toxic water can do that. So here are some basics.... Hexavelent chromium is, quite obviously, a form of the element chromium. The heavy metal is more commonly called chromium 6 and it's used in the production of stainless steel, pigments and protective coatings.
NEWS
December 17, 2001
Reported in Gene Trial Scientists have cured sickle-cell disease in a strain of mice by using a powerful gene therapy method that can replace nearly all diseased blood cells with healthy ones. Patients with sickle-cell disease have blood cells that deform when oxygen levels are low, creating painful blockages of blood vessels and producing organ damage. Researchers from Harvard University and MIT reported in the Dec. 14 issue of Science that they used a modified virus to treat the disease.
NEWS
February 24, 2001 | Reuters
U.S. researchers have produced laboratory mice with human brain cells, marking a potential step toward developing treatments for human brain disease such as Alzheimer's but promising to fuel fresh debate over bioengineering. The research was done at California biotechnology company StemCells Inc. "We are not re-creating a human brain.
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