November 15, 1987
Hooray for Kristine McKenna and the Calendar section ("Julian Schnabel--Artist as Bad Boy," Nov. 1)! Four reasons: For the courage, maturity, tolerance and general big-heartedness to publish the (all-too-typical and apparently only) response to the article on Schnabel. For avoiding the comfort of cynicism and regionalism. For appreciating the possibly inspirational aspects of Schnabel's success. And for keeping us informed about the competition. EDWARD W. RANDELL JR. Sherman Oaks
November 15, 2011 |
Alcoholism and other substance-use disorders appear strongly linked to a particular gene mutation, researchers reported Tuesday. Substance-use disorders are thought to arise from a combination of environmental or lifestyle factors and genetic characteristics. Identifying certain genes that are known to predispose people to the disease could be helpful in preventing drug addiction. Researchers have been working to identify some of the prominent gene mutations that could serve as markers.
April 23, 1999 |
As the front man for Chicago art-rock collective the Sea and Cake, Sam Prekop blends musical idioms until they dissolve into one another and become indistinguishable. But no matter how far-flung his experiments, Prekop always places a high premium on crafting subtle, deceptively simple melodies that please through repetition. Which is why his sensibility is ideally suited to the kind of quasi-jazz material that the guitarist showcased at the Troubadour on Wednesday.
February 2, 1996 |
When 8-year-old Rhoda calls Leroy, her decrepit apartment house janitor, "a very silly man," she's right on the money. But that's precisely the point--the sneering, black-toothed Leroy is played by a woman, Kris Strobeck, in Minneapolis-based Theatre 911's hilarious camp revival of Maxwell Anderson's "Bad Seed" at the St. Genesius Theatre. Then again, Rhoda has few grounds for complaint, seeing how this little sociopathic murderess is herself played by director Danny Schmitz, a 6-foot-tall man.
October 9, 2013 |
Scientists have discovered two gene mutations that they believe are associated with an increased risk of eating disorders. Anorexia nervosa and bulimia often run in families, but these eating disorders are complex, and it has proved difficult to identify the paths. But, using two families with very high incidences of eating disorders, scientists say they found rare mutations, one in each family, that were associated with the people who had the disorders. The study suggests that mutations that decrease the activity of a protein that turns on the expression of other genes - called a transcription factor - increase the risk.
October 25, 2003 |
U.S. and Japanese researchers said Thursday they had found a genetic mutation that causes obsessive-compulsive disorder and other mental illnesses and said some patients had a second mutation that made their conditions more severe. The finding, reported in the journal Molecular Psychiatry, could make it easier to discover treatments for the disorder, one of the top 10 leading causes of disability worldwide.
April 10, 1990 |
Elias Koteas is fortunate to be one of the few recognizable characters in "Teenage Mutant Ninja Turtles," except that anyone who sees him is likely to be under 15 years old. The shy, quiet, introspective actor was an unknown until this month. Now he is very well known indeed, thanks to his starring role in the biggest hit of the year. Koteas' involvement with the phenomenally successful action-comedy is a mixed blessing.
December 22, 2007 |
A mutation in a single gene may confer up to a 30% higher risk of getting amyotrophic lateral sclerosis, or Lou Gehrig's disease, offering a potential new target for drug research, Dutch scientists said this week. They said in the journal Nature Genetics that a variant in the DPP6 gene may give rise to ALS in people without a family susceptibility to the disease. Familial ALS, which accounts for 10% of ALS cases, has been linked with mutations in other genes.