CALIFORNIA | LOCAL
November 16, 1995 |
A UCLA psychiatrist has found the first clues to the mechanism of narcolepsy, the mysterious sleeping disorder that affects more than 250,000 Americans, causing them to lapse into sleep at inappropriate moments. They also have a characteristic muscle problem called cataplexy, a loss of muscle tone--often leading to collapse--caused by sudden excitement or even laughing. Working with a dog model of the disease, Dr. Jerome M.
CALIFORNIA | LOCAL
June 3, 1991 |
California researchers have found a new clue to the cause of narcolepsy, a neurological disorder characterized by intense sleepiness and episodes of cataplexy--an abrupt loss of muscle tone that is often triggered by sudden strong emotions. They have found that cataplexy is caused by the same brain cells that cause loss of muscle tone during so-called "rapid-eye-movement," or REM, sleep. Narcolepsy affects an estimated one in 2,000 people in the United States, a total of more than 125,000.
August 30, 2000 |
California researchers report that they have found the long-sought cause of narcolepsy, a mysterious sleep disorder that affects at least 125,000 Americans. The condition is caused by the death of a few cells deep within the brain, researchers from UCLA and Stanford report today. The results suggest that it may be possible to treat victims of the disorder, which is characterized by overwhelming sleepiness, and could lead to new ways of attacking other sleep disorders, experts said.
December 29, 1998 |
The Food and Drug Administration has approved a novel drug that keeps people with debilitating sleepiness awake and attentive yet has few of the side effects associated with caffeine, amphetamines and other commonly used stimulants. The drug, modafinil, was approved by the FDA for people with a serious sleep disorder called narcolepsy, which affects 1 out of 1,000 to 2,000 people and is characterized by sudden, overwhelming waves of intense sleepiness.
July 7, 1985
Scientists are hopeful that new studies showing narcolepsy to be genetically transmitted may lead to a cure for the sleep disorder that afflicts 250,000 Americans. The neurological disorder causes its victims to lose control over when they sleep and can result in hallucinations. Dr. William Dement, director of the Sleep Disorders Center at Stanford University, said that research in several countries has shown that defective genes are present in the blood of patients with narcolepsy.
December 4, 2001 |
Cephalon Inc., which makes neurological drugs, agreed to buy French drug maker Group Lafon for $450 million in cash. By gaining full control of Lafon's Provigil drug for narcolepsy, Cephalon expects to add about $80 million in sales and 3 cents a share to earnings in 2002. The West Chester, Pa.-based drug maker increased its 2002 earnings forecast to $1.03 a share. Sales will be $400 million to $410 million, Cephalon said.