CALIFORNIA | LOCAL
November 16, 1995 |
A UCLA psychiatrist has found the first clues to the mechanism of narcolepsy, the mysterious sleeping disorder that affects more than 250,000 Americans, causing them to lapse into sleep at inappropriate moments. They also have a characteristic muscle problem called cataplexy, a loss of muscle tone--often leading to collapse--caused by sudden excitement or even laughing. Working with a dog model of the disease, Dr. Jerome M.
CALIFORNIA | LOCAL
June 3, 1991 |
California researchers have found a new clue to the cause of narcolepsy, a neurological disorder characterized by intense sleepiness and episodes of cataplexy--an abrupt loss of muscle tone that is often triggered by sudden strong emotions. They have found that cataplexy is caused by the same brain cells that cause loss of muscle tone during so-called "rapid-eye-movement," or REM, sleep. Narcolepsy affects an estimated one in 2,000 people in the United States, a total of more than 125,000.
June 30, 2003 |
Tracy Heim's awareness of narcolepsy never extended much beyond the movie-screen image of people falling asleep in their soup. That was until she had three car accidents and started zoning out in mid-conversation during telephone calls at work. When the doctor she worked for suggested she might have narcolepsy, she dismissed the idea as absurd.
August 30, 2000 |
California researchers report that they have found the long-sought cause of narcolepsy, a mysterious sleep disorder that affects at least 125,000 Americans. The condition is caused by the death of a few cells deep within the brain, researchers from UCLA and Stanford report today. The results suggest that it may be possible to treat victims of the disorder, which is characterized by overwhelming sleepiness, and could lead to new ways of attacking other sleep disorders, experts said.
December 29, 1998 |
The Food and Drug Administration has approved a novel drug that keeps people with debilitating sleepiness awake and attentive yet has few of the side effects associated with caffeine, amphetamines and other commonly used stimulants. The drug, modafinil, was approved by the FDA for people with a serious sleep disorder called narcolepsy, which affects 1 out of 1,000 to 2,000 people and is characterized by sudden, overwhelming waves of intense sleepiness.
August 6, 1999 |
Two related genes known to affect hunger are also the long-sought cause of the excessive sleepiness of narcolepsy, according to Stanford and Texas researchers. The genes' effects were studied in dogs and mice, but the genes also have been found in humans. Researchers say the discovery may bring a narcolepsy cure within reach. Two reports on the subject are appearing in the journal Cell. The dog study is in today's issue and the mouse study is scheduled for publication Aug. 20.