September 26, 2013 |
Cocaine messes around with the brain. That scientific no-brainer has been getting more focused over the years, as neuroscientists identify key circuitry that can be reshaped by addiction. But an addiction researcher in Switzerland believes his colleagues may have been a bit too focused on the accelerator instead of the brakes - stimulation rather than disinhibition. Cocaine interferes with a natural inhibitor holding a reward neurotransmitter in balance, and without that brake, an unrestrained flow of dopamine sets off circuitry changes that have been tied to addictive behavior, according to a study published online Thursday in the journal Science.
June 1, 2013 |
As the brain fitness craze grows, so do the number of software programs that promise to boost mental skills. Here, we take a look at three of the largest companies in the digital brain health industry. Each offers trial games that users can play free: -- Lumosity With more than 35,000 registered users -- and more than 600 million game plays -- Lumosity has a strong presence in the brain-training circuit. Users' cognitive abilities are rated on a Brain Performance Index, or BPI, based on scores from tasks designed to test memory, attention, speed, flexibility and problem-solving skills.
February 13, 2013 |
Researchers at USC have made mice insensitive to near-freezing temperatures by deactivating select neurons, a development that could one day lead to new treatments for pain in humans. In a study published Tuesday in the Journal of Neuroscience, researchers used a bacterial toxin to kill neurons equipped with so-called TRPM8 channels, cellular structures that help relay sensations of cold. (The pathway is also responsible for sensing menthol, the cooling component of mint.) Neurons that sense heat and mechanical pain were left intact, however.
February 6, 2014 |
A generic blood pressure drug could prevent hyperactive brain cell firing associated with early stages of autism spectrum disorder, according to a new study. Injecting pregnant mice with Bumetanide, a diuretic, appears to correct a developmental switch flipped during childbirth that reverses the firing characteristics of neurons in newborns, according to a study published online Thursday in the journal Science. Bumetanide mimics the effects of oxytocin, a hormone released during labor that helps protect newborns from the stresses and complications of birth, the study found.
November 28, 2012 |
At the time of his death of an aortic aneurysm at age 76, Albert Einstein's brain was no bigger, and weighed no more, than the brain of an average older male. But beneath that unique organ's external folds and fissures, our universe was re-conceived. So not surprisingly, when photographs of Einstein's postmortem brain unexpectedly came to light recently, scientists were keen to find evidence of the genius that lay within. The result is a remarkably detailed look at the surface of Einstein's brain, published recently in the journal Brain.
November 20, 2013 |
The eyes may be the mirror of the soul, but for those with autism, the mouth will have to do. Researchers at Cedars-Sinai Medical Center isolated neurons in the brain's amygdala that respond to facial expressions, and tested patients with autism against those without. Both groups could correctly identify a "happy" or "fearful" face, a function long associated with the amygdala. But when the researchers examined which neurons fired in relation to areas of the face, they found that those with autism "read" the information from the mouth area more than from the eyes and seemed to be lacking a population of nerve cells that respond only to images of eyes.