February 6, 2014 |
A generic blood pressure drug could prevent hyperactive brain cell firing associated with early stages of autism spectrum disorder, according to a new study. Injecting pregnant mice with Bumetanide, a diuretic, appears to correct a developmental switch flipped during childbirth that reverses the firing characteristics of neurons in newborns, according to a study published online Thursday in the journal Science. Bumetanide mimics the effects of oxytocin, a hormone released during labor that helps protect newborns from the stresses and complications of birth, the study found.
November 28, 2012 |
At the time of his death of an aortic aneurysm at age 76, Albert Einstein's brain was no bigger, and weighed no more, than the brain of an average older male. But beneath that unique organ's external folds and fissures, our universe was re-conceived. So not surprisingly, when photographs of Einstein's postmortem brain unexpectedly came to light recently, scientists were keen to find evidence of the genius that lay within. The result is a remarkably detailed look at the surface of Einstein's brain, published recently in the journal Brain.
November 20, 2013 |
The eyes may be the mirror of the soul, but for those with autism, the mouth will have to do. Researchers at Cedars-Sinai Medical Center isolated neurons in the brain's amygdala that respond to facial expressions, and tested patients with autism against those without. Both groups could correctly identify a "happy" or "fearful" face, a function long associated with the amygdala. But when the researchers examined which neurons fired in relation to areas of the face, they found that those with autism "read" the information from the mouth area more than from the eyes and seemed to be lacking a population of nerve cells that respond only to images of eyes.
February 13, 2013 |
Researchers at USC have made mice insensitive to near-freezing temperatures by deactivating select neurons, a development that could one day lead to new treatments for pain in humans. In a study published Tuesday in the Journal of Neuroscience, researchers used a bacterial toxin to kill neurons equipped with so-called TRPM8 channels, cellular structures that help relay sensations of cold. (The pathway is also responsible for sensing menthol, the cooling component of mint.) Neurons that sense heat and mechanical pain were left intact, however.
June 6, 2013 |
If you lived during the early Cold War, you got nuked. On the other hand, you may have grown new brain cells. That's the take-away of research in the journal Cell that calculated the growth of brain cells in adult brains by using an isotope of carbon that was picked up by humans from the fallout due to above-ground nuclear testing from the late 1940s to 1963. Neuroscientists have shifted from an old view that you'll never have more neurons than you had when your brain was a pup. Studies have suggested that adult brains generate new neurons, particularly in the hippocampus, an area crucial to learning and memory.
October 23, 2012 |
Here's something for raw-food aficionados to chew on: Cooked food might be a big reason humans were able to grow such large brains compared to their body size, scientists say. If modern human ancestors had eaten only raw food, they'd have to regularly feed more than nine hours a day, according to a study published online Monday in Proceedings of the National Academy of Sciences. A pair of researchers from the Instituto Nacional de Neurociéncia Translacional in São Paulo, Brazil, decided to try and help explain why modern humans' brains were able to grow so large compared to their body size and why other primates' brains did not. They looked at the relative brain-to-neuron-counts of a host of primates, from owl monkeys to baboons.