February 6, 2014 |
A generic blood pressure drug could prevent hyperactive brain cell firing associated with early stages of autism spectrum disorder, according to a new study. Injecting pregnant mice with Bumetanide, a diuretic, appears to correct a developmental switch flipped during childbirth that reverses the firing characteristics of neurons in newborns, according to a study published online Thursday in the journal Science. Bumetanide mimics the effects of oxytocin, a hormone released during labor that helps protect newborns from the stresses and complications of birth, the study found.
November 28, 2012 |
At the time of his death of an aortic aneurysm at age 76, Albert Einstein's brain was no bigger, and weighed no more, than the brain of an average older male. But beneath that unique organ's external folds and fissures, our universe was re-conceived. So not surprisingly, when photographs of Einstein's postmortem brain unexpectedly came to light recently, scientists were keen to find evidence of the genius that lay within. The result is a remarkably detailed look at the surface of Einstein's brain, published recently in the journal Brain.
November 20, 2013 |
The eyes may be the mirror of the soul, but for those with autism, the mouth will have to do. Researchers at Cedars-Sinai Medical Center isolated neurons in the brain's amygdala that respond to facial expressions, and tested patients with autism against those without. Both groups could correctly identify a "happy" or "fearful" face, a function long associated with the amygdala. But when the researchers examined which neurons fired in relation to areas of the face, they found that those with autism "read" the information from the mouth area more than from the eyes and seemed to be lacking a population of nerve cells that respond only to images of eyes.
February 3, 2014 |
You wouldn't think that dissolving part of the brain, particularly one that helps hold the organ together, would help a gerbil rethink a problem. But that's exactly what a team of German scientists has done. Their results, published online Monday in the journal Proceedings of the National Academy of Sciences, suggest that a lot more is going on in the spaces between neurons, and an area of the brain once thought of as a simple processor may be more like a calculator. Researchers from the Leibniz Institute for Neurobiology in Magdeburg were focusing on a microscopic scaffold that stabilizes the synapses, the tiny gaps where electrochemical signals are relayed between neurons.
September 26, 2013 |
Cocaine messes around with the brain. That scientific no-brainer has been getting more focused over the years, as neuroscientists identify key circuitry that can be reshaped by addiction. But an addiction researcher in Switzerland believes his colleagues may have been a bit too focused on the accelerator instead of the brakes - stimulation rather than disinhibition. Cocaine interferes with a natural inhibitor holding a reward neurotransmitter in balance, and without that brake, an unrestrained flow of dopamine sets off circuitry changes that have been tied to addictive behavior, according to a study published online Thursday in the journal Science.
June 10, 2008
Fat cells: A June 2 Health section article on fat cells said that brain cells are never replaced. Although the body doesn't create new cells in the brain's cortex and cerebellum, it does continue to create cells, or neurons, in other parts of the brain.