February 6, 2014 |
A generic blood pressure drug could prevent hyperactive brain cell firing associated with early stages of autism spectrum disorder, according to a new study. Injecting pregnant mice with Bumetanide, a diuretic, appears to correct a developmental switch flipped during childbirth that reverses the firing characteristics of neurons in newborns, according to a study published online Thursday in the journal Science. Bumetanide mimics the effects of oxytocin, a hormone released during labor that helps protect newborns from the stresses and complications of birth, the study found.
June 3, 2013 |
Hyperactive brain cells firing together could be an early indicator of autism and developmental disabilities, a team of UCLA researchers has found. Networks of neurons were found to be firing in a highly synchronized and seemingly unrelenting fashion, even through sleep, in the brains of juvenile mice that have a genetic abnormality similar to one that causes mental retardation and autism symptoms in humans, according to the research published online Monday in Nature Neuroscience.
November 28, 2012 |
At the time of his death of an aortic aneurysm at age 76, Albert Einstein's brain was no bigger, and weighed no more, than the brain of an average older male. But beneath that unique organ's external folds and fissures, our universe was re-conceived. So not surprisingly, when photographs of Einstein's postmortem brain unexpectedly came to light recently, scientists were keen to find evidence of the genius that lay within. The result is a remarkably detailed look at the surface of Einstein's brain, published recently in the journal Brain.
February 13, 2013 |
Researchers at USC have made mice insensitive to near-freezing temperatures by deactivating select neurons, a development that could one day lead to new treatments for pain in humans. In a study published Tuesday in the Journal of Neuroscience, researchers used a bacterial toxin to kill neurons equipped with so-called TRPM8 channels, cellular structures that help relay sensations of cold. (The pathway is also responsible for sensing menthol, the cooling component of mint.) Neurons that sense heat and mechanical pain were left intact, however.
June 10, 2008
Fat cells: A June 2 Health section article on fat cells said that brain cells are never replaced. Although the body doesn't create new cells in the brain's cortex and cerebellum, it does continue to create cells, or neurons, in other parts of the brain.
August 2, 2011 |
It's all shrinking-brain stuff this week in the health news world, it seems. Yesterday, we reported that obesity (as well as smoking, diabetes and high blood pressure) in midlife causes brains to shrink at an accelerated clip. Today, we learn that dieting causes certain brain cells to start eating bits of themselves -- triggering a hunger response. Damned if you do, damned if you don't. This act of self-cannibalism was reported by scientists at the Albert Einstein College of Medicine in the journal Cell Metabolism . It occurs in mice. But there's a very good chance it would also happen in our heads as well, since many metabolic processes are very similar between our two species -- especially ancient important ones such as "eat more when you're burning more calories than you're taking in. " The neurons in question are specific ones in the hypothalamus that are involved in appetite regulation. What happens is this: The neurons in starved mice start chomping on themselves in a process known technically as autophagy ("self-eat")